Chmielnicka J, Komsta-Szumska E, Szymańska J A
Br J Ind Med. 1981 May;38(2):175-8. doi: 10.1136/oem.38.2.175.
In a group of 60 workers occupationally exposed to lead the blood and urine lead concentrations, haematocrit, ALA-D and arginase activities, and urinary 5-aminolaevulinic acid (ALA) and coproporphyrin concentrations, and kallikrein activity were determined. Correlation coefficients of -0.78 and 0.77 for Pb-B/ALA and Pb-B/arginase were found respectively for lead concentrations above 40 microgram/dl blood, and 0.83, 0.76, 0.74, and -0.64 for Pb-U/ALA, Pb-U/Cp-U, Pb-U/kallikrein, and Pb.U/kallikrein, respectively. It seems that the increase in serum arginase activity may be indicative of liver damage while the decrease in kallikrein activity may indicate kidney damage in workers exposed to lead.
对60名职业性接触铅的工人测定了血铅和尿铅浓度、血细胞比容、δ-氨基乙酰丙酸脱水酶（ALA-D）和精氨酸酶活性、尿5-氨基乙酰丙酸（ALA）和粪卟啉浓度以及激肽释放酶活性。血铅浓度高于40微克/分升时，血铅与ALA、血铅与精氨酸酶的相关系数分别为-0.78和0.77；尿铅与ALA、尿铅与尿粪卟啉、尿铅与激肽释放酶、尿铅与激肽释放酶的相关系数分别为0.83、0.76、0.74和-0.64。接触铅的工人血清精氨酸酶活性升高可能提示肝损伤，而激肽释放酶活性降低可能提示肾损伤。
