Raikhlin N T, Kvetnoĭ I M
Arkh Patol. 1977;39(5):74-80.
Current concepts of the APUD-system combining neuroendocrinal cells located in different organs are presented. The main feature of these cells is the capacity to accumulate precursors of biogenic amines, to decarboxylate them and to produce biogenic amines or polypeptide hormones. The problem of the development of tumours of these cells is discussed, and their morphological, histochemical and clinical features are described.
本文介绍了当前关于APUD系统的概念,该系统整合了位于不同器官的神经内分泌细胞。这些细胞的主要特征是能够积累生物胺前体、使其脱羧并产生生物胺或多肽激素。文中讨论了这些细胞肿瘤的发生问题,并描述了它们的形态学、组织化学和临床特征。