Al-Abri Mohammed A, Al-Harmeli Ahmed, Al-Habsi Mahmoud, Jaju Deepali
Sleep Medicine Unit, Department of Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman.
Oman Med J. 2020 Nov 15;35(6):e198. doi: 10.5001/omj.2020.94. eCollection 2020 Nov.
Continuous positive airway pressure (CPAP) compliance of > 4 hours per night has been considered acceptable to achieve clinical improvements in patients with obstructive sleep apnea (OSA). However, the factors determining CPAP adherence are unclear. This study aims to address the issue of acceptance and adherence to CPAP treatment in the Omani population and to determine the factors affecting adherence to CPAP.
This retrospective study included adult OSA patients who underwent polysomnography between January 2008 and December 2014 (n = 3046). Demographic information, Epworth Sleepiness Scale (ESS), apnea/hypopnea index (AHI), and desaturation events were collected from the sleep laboratory records. Subjects were grouped as CPAP users and CPAP non-users. CPAP users were divided into compliers (> 4 hours/night) and non-compliers (< 4 hours/night). Student's -test was used to find differences in CPAP users and non-users, compliers, and gender differences in CPAP users. The association of CPAP compliers and non-compliers with age, gender, AHI, ESS, and comorbidities were assessed using the chi-square test.
Out of the 90.0% patients advised CPAP treatment, 34.7% came for regular CPAP follow-up. Total CPAP compliers were 59.3% (n = 274). The CPAP users had higher age, high ESS, baseline AHI, and more oxygen desaturation events than CPAP non-users ( < 0.010). Among the CPAP users, females were significantly older than males and had more oxygen desaturation events. CPAP compliers had significantly higher baseline AHI and more oxygen desaturation events. There was no association between CPAP compliance and age, gender, AHI, ESS, or comorbidities.
CPAP users and compilers have severe OSA. CPAP acceptance and adherence are suboptimal and could not be predicted by age, gender, AHI, ESS, or comorbidities.
每晚持续气道正压通气(CPAP)使用时长大于4小时被认为是实现阻塞性睡眠呼吸暂停(OSA)患者临床改善的可接受标准。然而,决定CPAP依从性的因素尚不清楚。本研究旨在探讨阿曼人群对CPAP治疗的接受度和依从性问题,并确定影响CPAP依从性的因素。
这项回顾性研究纳入了2008年1月至2014年12月期间接受多导睡眠图检查的成年OSA患者(n = 3046)。从睡眠实验室记录中收集人口统计学信息、爱泼华嗜睡量表(ESS)、呼吸暂停/低通气指数(AHI)和血氧饱和度下降事件。受试者分为CPAP使用者和非使用者。CPAP使用者又分为依从者(每晚>4小时)和非依从者(每晚<4小时)。采用学生t检验来发现CPAP使用者和非使用者之间以及依从者之间的差异,以及CPAP使用者中的性别差异。使用卡方检验评估CPAP依从者和非依从者与年龄、性别、AHI、ESS和合并症之间的关联。
在被建议进行CPAP治疗的患者中,90.0%的患者前来进行CPAP定期随访。CPAP总依从者占59.3%(n = 274)。CPAP使用者比非使用者年龄更大、ESS得分更高、基线AHI更高,且血氧饱和度下降事件更多(P < 0.010)。在CPAP使用者中,女性明显比男性年龄大,且血氧饱和度下降事件更多。CPAP依从者的基线AHI明显更高,血氧饱和度下降事件更多。CPAP依从性与年龄、性别、AHI、ESS或合并症之间没有关联。
CPAP使用者和依从者患有严重的OSA。CPAP的接受度和依从性不理想,且无法通过年龄、性别、AHI、ESS或合并症来预测。