Home Hospice, Lower Silesian Oncology Center, Wrocław, Poland.
Eur Rev Med Pharmacol Sci. 2020 Nov;24(21):11128-11138. doi: 10.26355/eurrev_202011_23600.
To evaluate the association between satisfaction with life and Quality of Life (QoL) in lung cancer patients, and to analyze the correlations of selected variables with QoL.
250 patients with lung cancer were enrolled into the study, with a mean age of 63.2± 9.4, and who were treated at the Regional Lung Hospital in Poland between January and June 2019. 110 patients (43.9%) were moderately satisfied with their life (18-23 points from SWLS). 72 (28.8%) had a high level of satisfaction, and 68 (27.2%) had a low level of satisfaction with life.
Patients with a high level of satisfaction with life had a better QoL (p<0.001) and experienced less severe symptoms, with the exception of constipation, haemoptoe, soreness in the mouth, dysphagia, hair loss, and pain in the arms. Patients with a high level of satisfaction with life have a significantly lower intensity of behaviors associated with anxious preoccupation (p<0.001) and helplessness/hopelessness (p<0.001). Destructive coping styles increase as satisfaction with life decreases (p<0.001). Patients with a high level of satisfaction with life were more accepting of their illness (p<0.001).
Patients being treated for lung cancer have a moderate level of satisfaction with life. QoL is associated with satisfaction with life and increases depending on the level of satisfaction. Symptoms are less severe when patients are more satisfied with their life. Satisfaction with life was associated with acceptance of the illness and coping strategies. Not smoking, chest pain, time from diagnosis, performance status, and symptomatic treatment adversely affected satisfaction with life. Conversely, a lack of family history of cancer positively affected satisfaction with life.
评估肺癌患者生活满意度与生活质量（QoL）之间的关系，并分析选定变量与 QoL 的相关性。
本研究纳入了 2019 年 1 月至 6 月在波兰地区肺癌医院接受治疗的 250 例肺癌患者，平均年龄为 63.2±9.4 岁。其中 110 例（43.9%）对生活满意度中等（SWLS 得分为 18-23 分），72 例（28.8%）满意度高，68 例（27.2%）满意度低。
对生活满意度高的患者生活质量更好（p<0.001），症状较轻，除便秘、咯血、口腔疼痛、吞咽困难、脱发和手臂疼痛外。对生活满意度高的患者与焦虑困扰相关的行为强度显著降低（p<0.001）和无助/绝望（p<0.001）。随着生活满意度的降低，破坏应对方式的强度增加（p<0.001）。对生活满意度高的患者更能接受自己的疾病（p<0.001）。
接受肺癌治疗的患者对生活的满意度处于中等水平。QoL 与生活满意度相关，并且随着满意度的增加而提高。当患者对生活更满意时，症状会减轻。生活满意度与疾病的接受度和应对策略相关。不吸烟、胸痛、诊断时间、表现状态和对症治疗对生活满意度产生不利影响。相反，没有癌症家族史则对生活满意度产生积极影响。
