• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

辅助工具在牙周维护治疗中的疗效：一项系统文献综述与荟萃分析

The Efficacy of Adjunctive Aids in Periodontal Maintenance Therapy: A Systematic Literature Review and Meta-analysis.

作者信息

Ramanauskaite Egle, Sakalauskaite Urte Marija, Machiulskiene Vita

出版信息

Oral Health Prev Dent. 2020 Oct 13;18(4):889-910. doi: 10.3290/j.ohpd.a45406.

DOI:10.3290/j.ohpd.a45406
PMID:33215481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11654488/
Abstract

PURPOSE

To evaluate the efficacy of adjunctive aids to scaling and root planing (SRP) on clinical outcomes in treating periodontal patients included in regular periodontal maintenance programs.

MATERIALS AND METHODS

The electronic databases MEDLINE (Pubmed), EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched for relevant articles published up to 1st January, 2020. Randomised controlled clinical trials of SRP with or without the use of adjuncts and published in English were included. A meta-analysis using the random-effects model was performed on the selected qualifying articles.

RESULTS

Nineteen studies were included in the systematic review and sixteen in the meta-analysis. The overall effect of adjunctive aids was statistically significant for reduction in probing depth (PD) (0.376 mm, 95% CI [0.144 to 0.609]) and clinical attachment level (CAL) gain (0.207 mm, 95% CI [0.0728 to 0.340]). No statistically significant differences were observed for changes in bleeding on probing (BOP) (p > 0.05). Among the different adjuncts, statistically significant positive effects were demonstrated for adjunctive photodynamic therapy (PD reduction 0.908 mm, 95% CI [0.227 to 1.589] and CAL change (0.457 mm, 95% CI [0.133 to 0.782]) and tetracycline fibers (PD reduction 0.534 mm, 95% CI [0.290 to 0.778] and CAL gain 0.280 mm, 95% CI [0.0391 to 0.521]).

CONCLUSIONS

Despite high heterogeneity of the investigated data, based on the findings of a current systematic review, adjunctive aids (in particular, photodynamic therapy and tetracycline fibers) combined with SRP provide statistically significant clinical benefits compared to SRP alone. Due to the large number of included studies with high risk of bias, future studies should be based on adequate methodological procedures to improve the overall quality of reporting and to reduce the risk of bias.

摘要

目的

评估在常规牙周维护计划中，辅助器械用于龈下刮治和根面平整（SRP）对牙周病患者临床疗效的影响。

材料与方法

检索电子数据库MEDLINE（PubMed）、EMBASE和Cochrane对照试验中心注册库（CENTRAL），查找截至2020年1月1日发表的相关文章。纳入以英文发表的、关于使用或不使用辅助器械的SRP随机对照临床试验。对选定的合格文章进行随机效应模型的荟萃分析。

结果

系统评价纳入19项研究，荟萃分析纳入16项研究。辅助器械在降低探诊深度（PD）（0.376mm，95%CI[0.144至0.609]）和增加临床附着水平（CAL）（0.207mm，95%CI[0.0728至0.340]）方面的总体效果具有统计学意义。探诊出血（BOP）变化无统计学显著差异（p>0.05）。在不同的辅助器械中，辅助光动力疗法（PD降低0.908mm，95%CI[0.227至1.589]和CAL变化（0.457mm，95%CI[0.133至0.782]）以及四环素纤维（PD降低0.534mm，95%CI[0.290至0.778]和CAL增加0.280mm，95%CI[0.0391至0.521]）显示出统计学显著的积极效果。

结论

尽管研究数据存在高度异质性，但基于当前系统评价的结果，与单独的SRP相比，辅助器械（特别是光动力疗法和四环素纤维）联合SRP具有统计学显著的临床益处。由于纳入的大量研究存在高偏倚风险，未来的研究应基于适当的方法程序，以提高报告的整体质量并降低偏倚风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/1020ceeed760/ohpd-18-4-889-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/310214e8928f/ohpd-18-4-889-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/70d74579d9f5/ohpd-18-4-889-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/11dfbf99349e/ohpd-18-4-889-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/2dd08cadf947/ohpd-18-4-889-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/732ebd390ee4/ohpd-18-4-889-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f81b8bde8f5e/ohpd-18-4-889-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/2a15f1cc53cc/ohpd-18-4-889-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f9e40fb0ac32/ohpd-18-4-889-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/36c6f177522e/ohpd-18-4-889-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/1df33929607e/ohpd-18-4-889-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/75cdd16fb205/ohpd-18-4-889-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/927134e7c185/ohpd-18-4-889-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/216fcb496bd7/ohpd-18-4-889-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/61a3537c1400/ohpd-18-4-889-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/106194e458fc/ohpd-18-4-889-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/044fe5d8aee2/ohpd-18-4-889-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f8a60c77d89b/ohpd-18-4-889-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/1020ceeed760/ohpd-18-4-889-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/310214e8928f/ohpd-18-4-889-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/70d74579d9f5/ohpd-18-4-889-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/11dfbf99349e/ohpd-18-4-889-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/2dd08cadf947/ohpd-18-4-889-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/732ebd390ee4/ohpd-18-4-889-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f81b8bde8f5e/ohpd-18-4-889-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/2a15f1cc53cc/ohpd-18-4-889-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f9e40fb0ac32/ohpd-18-4-889-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/36c6f177522e/ohpd-18-4-889-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/1df33929607e/ohpd-18-4-889-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/75cdd16fb205/ohpd-18-4-889-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/927134e7c185/ohpd-18-4-889-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/216fcb496bd7/ohpd-18-4-889-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/61a3537c1400/ohpd-18-4-889-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/106194e458fc/ohpd-18-4-889-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/044fe5d8aee2/ohpd-18-4-889-g016.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/f8a60c77d89b/ohpd-18-4-889-g017.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f7a/11654488/1020ceeed760/ohpd-18-4-889-g018.jpg

相似文献

1
The Efficacy of Adjunctive Aids in Periodontal Maintenance Therapy: A Systematic Literature Review and Meta-analysis.辅助工具在牙周维护治疗中的疗效：一项系统文献综述与荟萃分析
Oral Health Prev Dent. 2020 Oct 13;18(4):889-910. doi: 10.3290/j.ohpd.a45406.
2
Full-mouth treatment modalities (within 24 hours) for chronic periodontitis in adults.成人慢性牙周炎的全口治疗模式（24小时内）
Cochrane Database Syst Rev. 2015 Apr 17;2015(4):CD004622. doi: 10.1002/14651858.CD004622.pub3.
3
Clinical effectiveness of adjunctive antimicrobial photodynamic therapy for residual pockets during supportive periodontal therapy: A systematic review and meta-analysis.辅助性抗菌光动力疗法在支持性牙周治疗中对残余牙周袋的临床疗效：一项系统评价和荟萃分析。
Photodiagnosis Photodyn Ther. 2017 Mar;17:127-133. doi: 10.1016/j.pdpdt.2016.11.011. Epub 2016 Nov 22.
4
Antiseptics as adjuncts to scaling and root planing in the treatment of periodontitis: a systematic literature review.牙周炎治疗中，刮治和根面平整辅助使用抗菌剂的系统文献回顾。
BMC Oral Health. 2020 May 18;20(1):143. doi: 10.1186/s12903-020-01127-1.
5
Local anti-infective therapy: pharmacological agents. A systematic review.局部抗感染治疗：药物制剂。一项系统评价
Ann Periodontol. 2003 Dec;8(1):79-98. doi: 10.1902/annals.2003.8.1.79.
6
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri-implant diseases.辅助抗菌光动力疗法治疗牙周病和种植体周围病。
Cochrane Database Syst Rev. 2024 Jul 12;7(7):CD011778. doi: 10.1002/14651858.CD011778.pub2.
7
Adjunctive systemic antimicrobials for the non-surgical treatment of periodontitis.辅助性全身用抗菌药物用于牙周炎的非手术治疗
Cochrane Database Syst Rev. 2020 Nov 16;11(11):CD012568. doi: 10.1002/14651858.CD012568.pub2.
8
Full-mouth treatment modalities (within 24 hours) for periodontitis in adults.成人牙周炎的全口治疗方法（24 小时内）。
Cochrane Database Syst Rev. 2022 Jun 28;6(6):CD004622. doi: 10.1002/14651858.CD004622.pub4.
9
The concomitant administration of systemic amoxicillin and metronidazole compared to scaling and root planing alone in treating periodontitis: =a systematic review=.全身性阿莫西林和甲硝唑联合使用与单纯龈下刮治及根面平整术治疗牙周炎的比较：一项系统评价
BMC Oral Health. 2016 Feb 29;16:27. doi: 10.1186/s12903-015-0123-6.
10
Clinical efficacy of photodynamic therapy adjunctive to scaling and root planing in the treatment of chronic periodontitis: A systematic review and meta-analysis.光动力疗法辅助龈下刮治和根面平整治疗慢性牙周炎的临床疗效：一项系统评价和荟萃分析
Photodiagnosis Photodyn Ther. 2017 Jun;18:119-127. doi: 10.1016/j.pdpdt.2017.01.183. Epub 2017 Feb 8.

引用本文的文献

1
Histological evaluation of nonsurgical periodontal treatment with and without the use of sodium hypochlorite / amino acids and cross-linked hyaluronic acid gels in dogs.犬类中使用和不使用次氯酸钠/氨基酸及交联透明质酸凝胶进行非手术牙周治疗的组织学评估
Clin Oral Investig. 2024 Apr 27;28(5):281. doi: 10.1007/s00784-024-05674-7.
2
Clinical evaluation of sodium hypochlorite/amino acids and cross-linked hyaluronic acid adjunctive to non-surgical periodontal treatment: a randomized controlled clinical trial.次氯酸钠/氨基酸和交联透明质酸辅助非手术牙周治疗的临床评价：一项随机对照临床试验。
Clin Oral Investig. 2023 Nov;27(11):6645-6656. doi: 10.1007/s00784-023-05271-0. Epub 2023 Sep 23.
3

本文引用的文献

1
Efficacy of alternative or additional methods to professional mechanical plaque removal during supportive periodontal therapy: A systematic review and meta-analysis.支持性牙周治疗期间替代或辅助专业机械菌斑清除方法的疗效：一项系统评价和荟萃分析。
J Clin Periodontol. 2020 Jul;47 Suppl 22:144-154. doi: 10.1111/jcpe.13269.
2
Supportive periodontal therapy in moderate-to-severe periodontitis patients: A two-year randomized clinical trial.支持性牙周治疗在中重度牙周炎患者中的应用：一项为期两年的随机临床试验。
J Clin Periodontol. 2019 Nov;46(11):1083-1093. doi: 10.1111/jcpe.13178. Epub 2019 Sep 2.
3
Clinical and microbiological effects of multiple applications of antibacterial photodynamic therapy in periodontal maintenance patients. A randomized controlled clinical study.
Non-surgical Periodontal Treatment: SRP and Innovative Therapeutic Approaches.
非手术牙周治疗：龈下刮治术及创新治疗方法。
Adv Exp Med Biol. 2022;1373:303-327. doi: 10.1007/978-3-030-96881-6_16.
牙周维护患者多次应用抗菌光动力疗法的临床和微生物学效果。一项随机对照临床研究。
Photodiagnosis Photodyn Ther. 2019 Sep;27:44-50. doi: 10.1016/j.pdpdt.2019.05.028. Epub 2019 May 21.
4
Short ultrasonic debridement with adjunctive low-concentrated hypochlorite/amino acid gel during periodontal maintenance: randomized clinical trial of 12 months.牙周维护期内应用低浓度次氯酸钠/氨基酸凝胶辅助短超声洁治的随机临床试验：12 个月的研究。
Clin Oral Investig. 2020 Jan;24(1):201-209. doi: 10.1007/s00784-019-02949-2. Epub 2019 May 11.
5
Maintenance therapy for teeth and implants.牙齿和种植体的维护治疗。
Periodontol 2000. 2019 Feb;79(1):190-199. doi: 10.1111/prd.12255.
6
Trehalose powder for subgingival air-polishing during periodontal maintenance therapy: A randomized controlled trial.使用海藻糖粉末进行牙周维护治疗时的龈下空气抛光：一项随机对照试验。
J Periodontol. 2019 Mar;90(3):263-270. doi: 10.1002/JPER.17-0403. Epub 2018 Nov 9.
7
Two-Year Randomized Clinical Trial of Adjunctive Minocycline Microspheres in Periodontal Maintenance.米诺环素微球辅助用于牙周维护的两年随机临床试验
J Dent Hyg. 2018 Aug;92(4):51-58.
8
Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.牙周炎：2017 年牙周病和种植体周围疾病分类世界研讨会工作组 2 的共识报告。
J Periodontol. 2018 Jun;89 Suppl 1:S173-S182. doi: 10.1002/JPER.17-0721.
9
Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.牙周健康和牙龈疾病及状况在完整和减少的牙周组织中的表现：2017 年世界牙周病和种植体周围疾病分类研讨会第 1 工作组的共识报告。
J Periodontol. 2018 Jun;89 Suppl 1:S74-S84. doi: 10.1002/JPER.17-0719.
10
Microbiological analysis and the outcomes of periodontal treatment with or without adjunctive systemic antibiotics-a retrospective study.微生物分析及牙周治疗的结果（辅助全身用抗生素与否）——一项回顾性研究。
Clin Oral Investig. 2018 Dec;22(9):3031-3041. doi: 10.1007/s00784-018-2392-3. Epub 2018 Feb 21.