Laboratoires Clarins, Pontoise, France.
Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Skin Res Technol. 2021 Jul;27(4):560-568. doi: 10.1111/srt.12984. Epub 2020 Nov 20.
Many factors relate to enlargement and visibility of facial pores. However, how enlargement relates to modification of the skin structure is still poorly analysed. Therefore, our aim was to characterise the visible features and the micro-environment of facial pores.
We recruited 160 women, half of them with normal-size facial pores, the other half presenting enlarged pores. We analysed their right cheek using standardised photography, in vivo reflectance microscopy and optical coherence tomography.
If the area of pores is indeed the most differentiating visible characteristic, enlarged facial pores are also denser and more contrasted. At the structural level, enlarged facial pores present a more regular organisation of keratinocytes, an irregular dermo-epidermal junction and a higher attenuation of collagen between the surface and deeper layers. Still, the most relevant alterations of enlarged facial pores are the presence of bright tubular structures surrounding hair follicles and enlarged hair shafts.
These observations suggest that alterations of the stroma could result in altered skin tensions, leading to the dilation of the infundibulum and enlarged hair shaft. The modified tension would also explain the more regular organisation of the keratinocytes and the irregular dermo-epidermal junction.
许多因素与面部毛孔的增大和可见度有关。然而,毛孔增大与皮肤结构的改变如何相关,仍未得到充分分析。因此,我们的目的是描述面部毛孔的可见特征和微环境。
我们招募了 160 名女性,其中一半的人面部毛孔正常大小,另一半的人面部毛孔增大。我们使用标准化摄影、活体反射显微镜和光学相干断层扫描对她们的右脸颊进行了分析。
如果毛孔的面积确实是最具区分性的可见特征,那么增大的面部毛孔也更加密集和对比度更高。在结构水平上,增大的面部毛孔呈现出更规则的角朊细胞排列、不规则的表皮-真皮连接以及在表面和深层之间胶原衰减更高。然而,增大的面部毛孔最相关的改变是存在围绕毛囊的明亮管状结构和增大的毛发轴。
这些观察结果表明,基质的改变可能导致皮肤张力的改变,导致漏斗部扩张和毛发轴增大。改变的张力也可以解释角朊细胞更规则的排列和表皮-真皮连接的不规则。