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利用地理服务区衡量美国基于人群的肾移植服务可及性

Using Geographic Catchment Areas to Measure Population-based Access to Kidney Transplant in the United States.

机构信息

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.

Emory Transplant Center, Emory University School of Medicine, Atlanta, GA.

出版信息

Transplantation. 2020 Dec;104(12):e342-e350. doi: 10.1097/TP.0000000000003369.

Abstract

BACKGROUND

Monitoring efforts to improve access to transplantation requires a definition of the population attributable to a transplant center. Previously, assessment of variation in transplant care has focused on differences between administrative units-such as states-rather than units derived from observed care patterns. We defined catchment areas (transplant referral regions [TRRs]) from transplant center care patterns for population-based assessment of transplant access.

METHODS

We used US adult transplant listings (2006-2016) and Dartmouth Atlas catchment areas to assess the optimal method of defining TRRs. We used US Renal Data System and Scientific Registry of Transplant Recipient data to compare waitlist- and population-based kidney transplant rates.

RESULTS

We identified 110 kidney, 67 liver, 85 pancreas, 68 heart, and 43 lung TRRs. Most patients were listed in their assigned TRR (kidney: 76%; liver: 75%; pancreas: 75%; heart: 74%; lung: 72%), although the proportion varied by organ (interquartile range for kidney, 65.7%-82.5%; liver, 58.2%-78.8%; pancreas, 58.4%-81.1%; heart, 63.1%-80.9%; lung, 61.6%-76.3%). Patterns of population- and waitlist-based kidney transplant rates differed, most notably in the Northeast and Midwest.

CONCLUSIONS

Patterns of TRR-based kidney transplant rates differ from waitlist-based rates, indicating that current metrics may not reflect transplant access in the broader population. TRRs define populations served by transplant centers and could enable future studies of how transplant centers can improve access for patients in their communities.

摘要

背景

监测改善器官移植可及性的努力需要确定一个器官移植中心的人口归因定义。以前,评估移植护理的差异主要集中在行政单位(如州)之间的差异上,而不是基于观察到的护理模式的单位之间的差异。我们根据移植中心的护理模式定义了集水区(移植转诊区[TRR]),以便对移植可及性进行基于人群的评估。

方法

我们使用美国成人移植清单(2006-2016 年)和达特茅斯地图集集水区来评估定义 TRR 的最佳方法。我们使用美国肾脏数据系统和移植受者科学登记处的数据来比较等待名单和基于人群的肾脏移植率。

结果

我们确定了 110 个肾脏、67 个肝脏、85 个胰腺、68 个心脏和 43 个肺 TRR。大多数患者都在其指定的 TRR 中列出(肾脏:76%;肝脏:75%;胰腺:75%;心脏:74%;肺:72%),尽管比例因器官而异(肾脏的四分位间距为 65.7%-82.5%;肝脏,58.2%-78.8%;胰腺,58.4%-81.1%;心脏,63.1%-80.9%;肺,61.6%-76.3%)。基于人群和基于等待名单的肾脏移植率模式不同,在东北地区和中西部地区最为明显。

结论

基于 TRR 的肾脏移植率模式与基于等待名单的率模式不同,这表明当前的指标可能无法反映更广泛人群的移植可及性。TRR 定义了移植中心服务的人群,并为未来研究移植中心如何提高其社区患者的可及性提供了可能。

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