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美国东南部离肾移植中心的距离与肾移植过程早期步骤的可及性。

Distance to Kidney Transplant Center and Access to Early Steps in the Kidney Transplantation Process in the Southeastern United States.

机构信息

Departments of Surgery and.

Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.

出版信息

Clin J Am Soc Nephrol. 2020 Apr 7;15(4):539-549. doi: 10.2215/CJN.08530719. Epub 2020 Mar 24.

Abstract

BACKGROUND AND OBJECTIVES

Access to kidney transplantation requires a referral to a transplant center for medical evaluation. Prior research suggests that the distance that a person must travel to reach a center might be a barrier to referral. We examined whether a shorter distance from patients' residence to a transplant center increased the likelihood of referral and initiating the transplant evaluation once referred.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Adults who began treatment for ESKD at any Georgia, North Carolina, or South Carolina dialysis facility from 1/1/2012 to 12/31/2015 were identified from the US Renal Data System. Referral (within 1 year of dialysis initiation) and evaluation initiation (within 6 months of referral) data were collected from all nine transplant centers located in that region. Distance was categorized as <15, 15-30, 31-60, 61-90, and >90 miles from the center of a patient's residential zip code to the nearest center. We used multilevel, multivariable-adjusted logistic regression to quantify the association between distance with referral and evaluation initiation.

RESULTS

Among 27,250 adult patients on incident dialysis, 9582 (35%) were referred. Among those referred, 58% initiated evaluation. Although patients who lived farther from a center were less likely to be referred, distance was not statistically significantly related to transplant referral: adjusted odds ratios of 1.08 (95% confidence interval, 0.96 to 1.22), 1.07 (95% confidence interval, 0.95 to 1.22), 0.96 (95% confidence interval, 0.84 to 1.10), and 0.87 (95% confidence interval, 0.74 to 1.03) for 15-30, 31-60, 61-90, and >90 miles, respectively, compared with <15 miles ( trend =0.05). There was no statistically significant association of distance and evaluation initiation among referred patients: adjusted odds ratios of 1.14 (95% confidence interval, 0.97 to 1.33), 1.12 (95% confidence interval, 0.94 to 1.35), 1.04 (95% confidence interval, 0.87 to 1.25), and 0.89 (95% confidence interval, 0.72 to 1.11) for 15-30, 31-60, 61-90, and >90 miles, respectively, compared with <15 miles ( trend =0.70).

CONCLUSIONS

Distance from residence to transplant center among patients undergoing long-term dialysis in the southeastern United States was not associated with increased likelihood of referral and initiating transplant center evaluation.

摘要

背景与目的

接受肾移植需要转介到移植中心进行医学评估。先前的研究表明,患者必须前往中心的距离可能是转介的障碍。我们研究了距离患者居住地更近是否会增加转介的可能性,并在转介后增加开始移植评估的可能性。

设计、地点、参与者和测量:从美国肾脏数据系统中确定了 2012 年 1 月 1 日至 2015 年 12 月 31 日期间在佐治亚州、北卡罗来纳州或南卡罗来纳州任何透析机构开始接受终末期肾病治疗的成年人。从该地区的所有 9 个移植中心收集了转介(透析开始后 1 年内)和评估开始(转介后 6 个月内)的数据。距离分为<15、15-30、31-60、61-90 和>90 英里,从患者居住的邮政编码中心到最近的中心。我们使用多水平、多变量调整的逻辑回归来量化距离与转介和评估开始之间的关联。

结果

在 27250 名接受新透析治疗的成年患者中,有 9582 名(35%)被转介。在被转介的患者中,有 58%开始接受评估。尽管距离中心较远的患者转介的可能性较低,但距离与移植转介并无统计学显著相关性:调整后的优势比分别为 1.08(95%置信区间,0.96 至 1.22)、1.07(95%置信区间,0.95 至 1.22)、0.96(95%置信区间,0.84 至 1.10)和 0.87(95%置信区间,0.74 至 1.03),<15 英里(趋势=0.05)。在接受转介的患者中,距离与评估开始之间没有统计学显著的关联:调整后的优势比分别为 1.14(95%置信区间,0.97 至 1.33)、1.12(95%置信区间,0.94 至 1.35)、1.04(95%置信区间,0.87 至 1.25)和 0.89(95%置信区间,0.72 至 1.11),<15 英里(趋势=0.70)。

结论

在美国东南部接受长期透析治疗的患者中,居住地到移植中心的距离与增加转介和开始移植中心评估的可能性无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e48e/7133136/c5ee3854244d/CJN.08530719absf1.jpg

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