Department of Ophthalmology, American-Sino Women's & Children's Hospital, Shanghai, China.
Department of Ophthalmology, Southwest Hospital/Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Ocul Immunol Inflamm. 2022 Feb 17;30(2):402-408. doi: 10.1080/09273948.2020.1800751. Epub 2020 Nov 20.
To describe the characteristics seen on multispectral imaging (MSI) in patients with punctate inner choroidopathy (PIC) and choroidal neovascularisation (CNV) and compare the findings with current standard multimodal imaging techniques.
This is a retrospective observational case series of 10 patients with PIC complicated by CNV that underwent multimodal retinal imaging examinations.
Twelve eyes of 10 patients were included. CNV was identified in 11 of the 12 eyes (91.7%) by MSI with nodular or trunk-like hyperreflectance on retinal oxy/deoxyhemoglobin map. MSI revealed choroidal vasculature around CNV in 91.7% eyes and pathological changes including retinal pigment epithelial atrophy and melanin disruption of punctate lesions in all eyes.
MSI helps in noninvasively detecting CNV in PIC patients and observing associated changes in choroidal vasculature. This imaging technique is also a promising tool for better tracking pathological changes of PIC lesions complementary to current standard multimodal imaging modalities.
描述斑点状内层脉络膜病变（PIC）合并脉络膜新生血管（CNV）患者的多光谱成像（MSI）所见特征，并将这些发现与当前的标准多模态成像技术进行比较。
这是一项回顾性观察性病例系列研究，纳入了 10 例经多模态视网膜成像检查证实为 PIC 合并 CNV 的患者。
共纳入 10 例患者的 12 只眼。12 只眼中的 11 只（91.7%）通过 MSI 检测到 CNV，视网膜氧/脱氧血红蛋白图上可见结节状或主干状高反射。91.7%的眼通过 MSI 显示了 CNV 周围的脉络膜血管，所有眼均观察到了包括视网膜色素上皮萎缩和斑点状病变中黑色素破坏在内的病理性改变。
MSI 有助于非侵入性地检测 PIC 患者的 CNV，并观察脉络膜血管的相关变化。这种成像技术也有望成为一种有前途的工具，通过与当前的标准多模态成像方式互补，更好地跟踪 PIC 病变的病理变化。
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