Blokhin N N, Efetov V M, Klimenkov A A, Patiutko Iu I
Vopr Onkol. 1987;33(12):27-33.
The study was based on the data obtained from a long-term follow-up of 2840 cases of various surgical pathology of the stomach, gastroscopic examination of 1112 surgically-treated patients, experiments on stomach carcinogenesis, clinical and experimental studies on lymph drainage pathways and analysis of the results of 296 radical operations for cancer of the gastric stump. The following aspects of research in cancer of operated stomach were suggested: (1) risk of cancer development in operated stomach; (2) factors contributing to tumorigenesis; (3) biologic peculiarities of growth of gastric stump tumors as well as lymph drainage pathways, and (4) organization of follow-up and development of methods for diagnosis and treatment of the said pathology. The results of the study outlined vistas in prevention of cancer of the gastric stump. Adequate methods of diagnosis and treatment of this grave pathology were developed which was followed by a decrease in postoperative lethality and in increase in 5-year survival rate--to 8.5 and 26.4%, respectively.
该研究基于对2840例胃各种手术病理病例的长期随访、对1112例手术治疗患者的胃镜检查、胃癌发生实验、淋巴引流途径的临床和实验研究以及对296例胃残端癌根治手术结果的分析。提出了关于胃手术后癌症研究的以下几个方面：（1）胃手术后癌症发生的风险；（2）促成肿瘤发生的因素；（3）胃残端肿瘤生长的生物学特性以及淋巴引流途径，以及（4）随访的组织和所述病理诊断与治疗方法的开发。该研究结果勾勒出了胃残端癌预防的前景。开发了针对这种严重病理状况的适当诊断和治疗方法，随后术后死亡率降低，5年生存率提高——分别达到8.5%和26.4%。
