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一名近期前往刚果且出现谵妄症状的患者患脑型疟疾:病例报告

Cerebral Malaria in a Patient with Recent Travel to the Congo Presenting with Delirium: A Case Report.

作者信息

Roberson Megan T, Smith Austin T

机构信息

Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, Tennessee.

出版信息

Clin Pract Cases Emerg Med. 2020 Nov;4(4):533-536. doi: 10.5811/cpcem.2020.8.47995.

DOI:10.5811/cpcem.2020.8.47995
PMID:33217265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7676766/
Abstract

INTRODUCTION

Cerebral malaria, a syndrome of altered consciousness, is a rare and severe neurologic complication resulting from Plasmodium falciparum. Historically, cerebral malaria has been seen more frequently in children rather than adults. To complicate the diagnosis, cerebral malaria has few specific symptoms and neurologic findings can vary with each case.

CASE REPORT

We describe a case of a 61-year-old male who returned from the Democratic Republic of Congo and presented to the emergency department with dehydration, fatigue, and intermittent confusion. He was ultimately diagnosed with cerebral malaria caused by P. falciparum.

CONCLUSION

Even with close monitoring and appropriate treatment, cerebral malaria carries a severe risk of long-term neurocognitive deficits and a high mortality rate.

摘要

引言

脑型疟疾是一种意识改变综合征,是由恶性疟原虫引起的罕见且严重的神经系统并发症。从历史上看,脑型疟疾在儿童中比在成人中更常见。使诊断复杂化的是,脑型疟疾几乎没有特定症状,而且神经系统表现因病例而异。

病例报告

我们描述了一例61岁男性病例,该患者从刚果民主共和国返回后到急诊科就诊,伴有脱水、疲劳和间歇性意识模糊。他最终被诊断为恶性疟原虫引起的脑型疟疾。

结论

即使进行密切监测和适当治疗,脑型疟疾仍有长期神经认知缺陷的严重风险和高死亡率。

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Manual exchange transfusion for severe imported falciparum malaria: a retrospective study.手工换血治疗重症输入性恶性疟:一项回顾性研究。
Malar J. 2018 Jan 16;17(1):32. doi: 10.1186/s12936-018-2174-z.
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Stem cell therapy: a novel treatment option for cerebral malaria?干细胞疗法:治疗脑型疟疾的一种新选择?
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