Gilsdorf Christopher B, Davis Hillary E
University of Tennessee Medical Center, Department of Emergency Medicine, Knoxville, Tennessee.
University of Tennessee Medical Center, Department of Family Medicine, Knoxville, Tennessee.
Clin Pract Cases Emerg Med. 2020 Nov;4(4):564-568. doi: 10.5811/cpcem.2020.7.48317.
In patients with known malignancy and possible intracranial metastatic disease who are receiving treatment with therapeutic anticoagulation, limited data exist regarding risk of intracranial bleeding.
We present a case of a 64-year-old female with known lung malignancy, evidence of possible metastatic disease, and bilateral deep vein thrombosis, who suffered severe intracranial hemorrhage following initiation of therapeutic anticoagulation. Current guidelines, available risk- stratification tools, and treatment options with their risks are discussed.
In patients with known or suspected intracranial metastatic disease, clinical decision tools can assist both the clinician and the patient in weighing risks and benefits of anticoagulation.
在已知患有恶性肿瘤且可能存在颅内转移疾病并接受治疗性抗凝治疗的患者中,关于颅内出血风险的数据有限。
我们报告一例64岁女性患者,已知患有肺癌,有可能发生转移疾病的证据,且患有双侧深静脉血栓形成,在开始治疗性抗凝治疗后发生了严重颅内出血。文中讨论了当前指南、现有的风险分层工具以及具有相应风险的治疗选择。
在已知或疑似患有颅内转移疾病的患者中,临床决策工具可帮助临床医生和患者权衡抗凝治疗的风险与益处。