University of Massachusetts School of Medicine, Worcester, Massachusetts; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.
Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
J Am Acad Dermatol. 2021 Feb;84(2):247-255. doi: 10.1016/j.jaad.2020.11.001. Epub 2020 Nov 17.
Patch testing is the criterion standard for diagnosing allergic contact dermatitis. Causative allergens differ between children and adults, necessitating the development of pediatric-specific patch test series. The Pediatric Baseline Series was developed in 2018 through expert consensus and includes relevant pediatric allergens that dermatologists can use in practice. Obstacles in patch testing, such as the need for multiple office visits, length of patch application, and avoidance of sweat and water on the testing area, are particularly challenging for the pediatric population, and several strategies are proposed. Aside from formal patch testing, alternatives like the repeat open application test and empiric allergen avoidance can be helpful in children. The key to management of allergic contact dermatitis is allergen avoidance, with emphasis on the need to properly identify causative allergens. Continued data collection through registries allows for a better understanding of the diagnosis and management of pediatric allergic contact dermatitis.
斑贴试验是诊断变应性接触性皮炎的金标准。儿童和成人的致敏原不同,因此需要开发专门针对儿科的斑贴试验系列。儿科基础系列于 2018 年通过专家共识制定,包括皮肤科医生在实践中可以使用的相关儿科过敏原。斑贴试验存在一些障碍,例如需要多次就诊、贴片应用时间长以及避免测试区域出汗和沾水,这些对儿科人群来说特别具有挑战性,因此提出了一些策略。除了正式的斑贴试验外,重复开放应用试验和经验性过敏原回避等替代方法在儿童中也可能有帮助。变应性接触性皮炎的关键是过敏原回避,重点是需要正确识别致敏原。通过注册中心不断收集数据,可以更好地了解儿科变应性接触性皮炎的诊断和管理。