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2017 - 2022年儿童过敏性接触性皮炎的回顾性研究

A Retrospective Study of Pediatric Allergic Contact Dermatitis from 2017-2022.

作者信息

Pixley Jessica N, Kontzias Christina, Tao Rachel E, Massey Lauren, Mcpeeks Kimberly, Neighbors Katherine, Srivastava Radhika, Feldman Steven R, Burkhart Craig

机构信息

Department of Dermatology, Wake Forest University School of Medicine, 4618 Country Club Road, Winston-Salem, NC, 27104, USA.

Burkhart Pediatric and Adolescent Dermatology, Cary, NC, USA.

出版信息

Dermatol Ther (Heidelb). 2025 Feb;15(2):445-452. doi: 10.1007/s13555-024-01314-w. Epub 2025 Jan 30.

Abstract

OBJECTIVES

Allergic contact dermatitis occurs frequently in children. The proportion of children of color in the US is increasing, and racial and ethnic minority representation is important in pediatric allergic contact dermatitis research. The objectives of our study were to identify differences in age, sex, race and ethnicity among pediatric patch tests obtained from 2017 to 2022.

METHODS

A total of 792 pediatric patients were evaluated, and patch test differences were analyzed among age, sex, race and ethnicity groups.

RESULTS

Children in the age group 0-5 years had the highest number of positive reactions, and propolis was the most frequent allergen among females and in children in the age groups 6-11 years and 12-18 years. Carmine was the most frequent allergen among males and among children in the age group 1-5 years. Risk of sensitivity to multiple allergens varied with race and ethnicity.

CONCLUSIONS

The risk of patch test positivity to multiple allergens varied within the demographic groups evaluated. The etiology of these differences is likely multi-factorial and includes differences in exposure patterns and disparities in access.

摘要

目的

过敏性接触性皮炎在儿童中频繁发生。美国有色人种儿童的比例在增加,种族和少数民族代表性在儿科过敏性接触性皮炎研究中很重要。我们研究的目的是确定2017年至2022年获得的儿科斑贴试验在年龄、性别、种族和民族方面的差异。

方法

共评估了792名儿科患者,并分析了年龄、性别、种族和民族组之间的斑贴试验差异。

结果

0至5岁年龄组的儿童阳性反应数量最多,蜂胶是女性以及6至11岁和12至18岁年龄组儿童中最常见的变应原。胭脂红是男性以及1至5岁年龄组儿童中最常见的变应原。对多种变应原敏感的风险因种族和民族而异。

结论

在评估的人口群体中,对多种变应原斑贴试验阳性的风险各不相同。这些差异的病因可能是多因素的,包括接触模式的差异和获取机会的不平等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35c8/11832819/b7e290590275/13555_2024_1314_Fig1_HTML.jpg

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