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老挝牙医中的乙型肝炎病毒:一项横断面血清学研究。

Hepatitis B virus in Lao dentists: A cross-sectional serological study.

机构信息

Lao Tropical and Public Health Institute, Ministry of Health, Vientiane, Lao People's Democratic Republic.

Institut Pasteur du Laos, Vientiane, Lao People's Democratic Republic.

出版信息

Ann Hepatol. 2021 May-Jun;22:100282. doi: 10.1016/j.aohep.2020.10.010. Epub 2020 Nov 17.

Abstract

INTRODUCTION AND OBJECTIVES

Hepatitis B virus (HBV) is endemic in Lao PDR, with up to 10% chronic infections in adults. Dentists have high risk of exposure and transmission to their patients. The aim was to investigate the serological profiles of vaccination, exposure and susceptibility to HBV. In addition, we determined the knowledge, attitude and practice (KAP) of Lao dentists toward HBV.

MATERIALS AND METHODS

Dentists and dental assistants were recruited from 186 private dental clinics in Vientiane Capital. They completed a KAP questionnaire and serum was tested by ELISA for HBV markers (anti-HB surface antigen, anti-core antigen, HBV surface antigen).

RESULTS

206 dentists and 111 dental workers aged between 18-63 years were included. Serology data showed that 37.8% had previous exposure (49.0% of males and 32.4% of females) and 5.0% were chronically infected (7.7% of males and 3.8% of females). Less than 15% had serological evidence of vaccination and 66.8% were unprotected against infection. Knowledge of HBV was mostly low, for example 61.8% were aware of the childhood HBV vaccine. Just over half said that they should give dental care to HBV carriers. About one quarter reported accidental blood exposure during the last 6 months but knowledge about procedures after exposure was low.

CONCLUSIONS

Lao dentists are at high risk of occupational exposure to HBV but have low awareness and serological protection. There is a need to introduce mandatory vaccination, to strengthen occupational health in health care providers and to further develop the academic curricula of dental students.

摘要

简介和目的

乙型肝炎病毒(HBV)在老挝普遍存在,成年人慢性感染率高达 10%。牙医在接触和传播给患者方面存在较高的风险。本研究旨在调查老挝牙医的疫苗接种、HBV 暴露和易感性的血清学特征。此外,我们还确定了老挝牙医对 HBV 的知识、态度和实践(KAP)。

材料和方法

从万象首都的 186 家私人牙科诊所招募牙医和牙科助理。他们填写了 KAP 问卷,通过 ELISA 检测血清中的 HBV 标志物(HBV 表面抗原、核心抗原、表面抗原)。

结果

共纳入 206 名牙医和 111 名 18-63 岁的牙科工作者。血清学数据显示,37.8%有既往暴露史(男性占 49.0%,女性占 32.4%),5.0%为慢性感染者(男性占 7.7%,女性占 3.8%)。不到 15%的人有疫苗接种的血清学证据,66.8%的人未受感染保护。对 HBV 的了解大多较低,例如,61.8%的人知道儿童乙肝疫苗。超过一半的人表示他们应该为 HBV 携带者提供牙科护理。约四分之一的人报告在过去 6 个月内发生过意外的血液暴露,但对暴露后的处理程序知之甚少。

结论

老挝牙医面临着职业性暴露于 HBV 的高风险,但他们的意识和血清保护水平较低。需要引入强制性疫苗接种,加强医疗保健提供者的职业健康,并进一步发展牙科学生的学术课程。

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