Zhou Ke-Lin, Dong Shuo, Guo Sheng, Dai Xiao-Hui, Yang Jing-Yi, Liu Yang, Mi Bao-Lai, Wang Shao-Wei, Fu Guo-Bing, Wei Pei-Dong
Dongfang Hospital of Beijing University of Chinese Medicine.
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Medicine (Baltimore). 2020 Nov 20;99(47):e23347. doi: 10.1097/MD.0000000000023347.
Chronic atrophic gastritis (CAG) is an established precursor of gastric carcinoma with high prevalence worldwide. It is a typical complex gastro-intestinal disease with multiple influence factors, of which exact mechanisms remain unelucidated. Therefore, an ideal strategy to relieve CAG is urgently needed. In recent years, massage therapy has been increasingly accepted by CAG patients due to its lower costs, fewer unwanted side effects and safety for clinical use. In this systematic review, we aim to evaluate the effectiveness and safety of massage therapy for patients with chronic atrophic gastritis.
We will search the following electronic databases for randomized controlled trials to evaluate the effectiveness and safety of massage therapy in treating chronic atrophic gastritis: Wanfang and Pubmed Database, China National Knowledge Infrastructure Database, Cochrane Central register of controlled trials, Cumulative Index of Nursing and Allied Health Literature, and Excerpta Medica database. Each database will be searched from inception to September 2020. The entire process will include study selection, data extraction, risk of bias assessment, and meta-analyses.
This proposed study will evaluate the effectiveness and safety of massage therapy for patients with chronic atrophic gastritis. The outcomes will include changes in CAG relief and adverse effect.
This proposed systematic review will evaluate the existing evidence on the effectiveness and safety of massage therapy for patients with chronic atrophic gastritis.
The results of this review will be disseminated through peer-reviewed publication. Because all of the data used in this systematic review and meta-analysis has been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process.
慢性萎缩性胃炎（CAG）是一种公认的胃癌前体疾病，在全球范围内发病率很高。它是一种典型的具有多种影响因素的复杂胃肠道疾病，其确切机制仍未阐明。因此，迫切需要一种理想的缓解CAG的策略。近年来，按摩疗法因其成本较低、副作用较少且临床使用安全，越来越受到CAG患者的接受。在本系统评价中，我们旨在评估按摩疗法对慢性萎缩性胃炎患者的有效性和安全性。
我们将检索以下电子数据库以评估按摩疗法治疗慢性萎缩性胃炎的有效性和安全性：万方数据库、PubMed数据库、中国知网数据库、Cochrane对照试验中心注册库、护理学与健康照护领域累积索引数据库和医学文摘数据库。每个数据库将从建库至2020年9月进行检索。整个过程将包括研究选择、数据提取、偏倚风险评估和荟萃分析。
本拟进行的研究将评估按摩疗法对慢性萎缩性胃炎患者的有效性和安全性。结局指标将包括CAG缓解情况和不良反应的变化。
本拟进行的系统评价将评估现有关于按摩疗法治疗慢性萎缩性胃炎有效性和安全性的证据。
本评价结果将通过同行评审发表进行传播。由于本系统评价和荟萃分析中使用的所有数据均已发表，因此本评价无需伦理批准。此外，在评价过程中所有数据将进行匿名分析。
