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化学化合物和生物活性:属的综述。

Chemical Compounds and Biologic Activities: A Review of Genus.

机构信息

Laboratório de Ciências Químicas, Centro de Ciências e Tecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 20000-000, Brazil.

Instituto Federal de Santa Catarina, Campus Criciúma, Criciúma 88800-000, Brazil.

出版信息

Molecules. 2020 Nov 18;25(22):5401. doi: 10.3390/molecules25225401.

Abstract

The genus P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species. These activities are mainly related to limonoids, a characteristic class of compounds in this family. Therefore, the aim of this review is to perform a survey of the citations in the literature on the genus species. Articles were found on quantitative and qualitative phytochemical studies of the species, revealing the chemical compounds identified, such as aliphatics acid and alcohol, flavonoids, tocopherol, monoterpenes, sesquiterpenes, triterpenes, cycloartanes, steroids, and limonoids. Although some activities were tested, the majority of studies focused on the insecticidal, antifeedant, or insect growth inhibitor activities of this genus. Nonetheless, the most promising activities were related to their antimalarial and antitripanocidal effects, although further investigations are still needed.

摘要

该属 P. Browne,属于楝科,有十八个种。由于木材的质量,这个属的树木具有经济意义,并且由于与其他楝科物种相关的生物活性而成为研究的焦点。这些活动主要与柠檬苦素有关,这是该科的一个特征类化合物。因此,本综述的目的是对该属物种的文献引文进行调查。发现了关于 物种的定量和定性植物化学研究的文章,揭示了所鉴定的化学化合物,如脂肪族酸和醇、类黄酮、生育酚、单萜、倍半萜、三萜、环阿尔烷、甾体和柠檬苦素。尽管已经测试了一些活性,但大多数研究集中在该属的杀虫、拒食或昆虫生长抑制剂活性上。尽管如此,最有前途的活性与它们的抗疟和抗锥虫效果有关,尽管仍需要进一步的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c167/7699174/81b071b0903b/molecules-25-05401-g001.jpg

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