运动疗法在乳腺癌幸存者中的应用及其对炎症特征的影响：叙事性综述。
Application of physical exercise therapies in breast cancer survivors and their effects on the inflammatory profile: A narrative review.
机构信息
Institute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Health Sciences Institute, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.
出版信息
J Bodyw Mov Ther. 2020 Oct;24(4):536-545. doi: 10.1016/j.jbmt.2020.08.002. Epub 2020 Sep 6.
BACKGROUND
One of the adverse effects of cancer treatments is the exacerbation of inflammation, which generates numerous limitations and contributes to the development of several comorbidities and the recurrence of cancer itself. Physical exercise (PE) has been proposed as an efficient complementary strategy to combat the inflammatory effects of oncological treatments and to prevent the development of comorbidities, but its adequate application in breast cancer survivors (BCS) requires the establishment of consensuses and practical recommendations.
OBJECTIVE
This study aimed to review the randomized controlled trials that evaluated the influence of PE in the inflammatory profile of BCS.
METHODS
The search for articles published between 1999 and 2020 was done in PsycINFO, PubMed, Cochrane, Science Direct, and Scopus databases.
RESULTS
Current knowledge reveals the effectiveness of PE in the functional independence and health of BCS. Evidence of the capacity of PE to improve the inflammatory profile and the immune response in BCS has also been described. However, the heterogeneity of the studies regarding structural training variables, types of exercise, stages of intervention, and severity of the disease, still do not allow the establishment of precise guidelines for the prescription and progression of exercise to improve the inflammatory process in BCS.
DISCUSSION
. This review suggests a possible strategy to be used in the assessment, training prescription, and rehabilitation of BCS, to support the development of new studies and the work of exercise professionals in the prescription and application of physical training to improve health and inflammatory status in BCS.
背景
癌症治疗的副作用之一是炎症的加剧，这会产生许多限制，并导致多种合并症的发展和癌症本身的复发。体育锻炼（PE）已被提议作为一种有效的补充策略，以对抗肿瘤治疗的炎症作用，并预防合并症的发生，但在乳腺癌幸存者（BCS）中适当应用需要建立共识和实际建议。
目的
本研究旨在综述评估 PE 对 BCS 炎症谱影响的随机对照试验。
方法
在 PsycINFO、PubMed、Cochrane、Science Direct 和 Scopus 数据库中搜索 1999 年至 2020 年发表的文章。
结果
目前的知识揭示了 PE 在 BCS 的功能独立性和健康方面的有效性。也描述了 PE 改善 BCS 炎症谱和免疫反应的能力的证据。然而，关于结构训练变量、运动类型、干预阶段和疾病严重程度的研究存在异质性，仍然不能为改善 BCS 炎症过程的运动处方和进展制定精确的指南。
讨论
。这篇综述为 BCS 的评估、训练处方和康复提供了一种可能的策略，以支持新研究的开展和运动专业人员在 BCS 健康和炎症状况改善方面的处方和应用体育锻炼。
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