The Thyroid, Head and Neck Cancer (THANC) Foundation, New York, NY, USA.
Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai Hospital, Mount Sinai Beth Israel, New York, NY, USA.
Head Neck. 2021 Mar;43(3):E20-E26. doi: 10.1002/hed.26552. Epub 2020 Nov 21.
Liposarcomas are the second most common type of soft tissue sarcomas. Typically, myxoid liposarcomas have a metastatic rate of 10%, usually involving the retroperitoneal space, abdomen, and spine. Metastasis to the thyroid is extremely rare.
DESIGN/METHOD: A 62-year-old male with a history of metastatic myxoid liposarcoma in his right thigh presented to our clinic for evaluation of a thyroid nodule incidentally identified on a CT scan. A subsequent FNA biopsy was suggestive of a metastatic liposarcoma.
The patient underwent a left thyroid lobectomy and final pathology confirmed a grade II/III metastatic myxoid liposarcoma that measured 3.3 cm. The patient tolerated the procedure well.
Our case highlights the role of a patient's medical history when evaluating thyroid nodules to optimize accurate diagnosis, as liposarcomas do not typically metastasize to the thyroid. We also provide an updated review of the literature on all cases of metastatic sarcomas to the thyroid.
脂肪肉瘤是第二常见的软组织肉瘤类型。典型的黏液样脂肪肉瘤转移率为 10%，通常累及腹膜后腔、腹部和脊柱。转移到甲状腺极为罕见。
方法/设计：一名 62 岁男性，曾在右侧大腿患有转移性黏液样脂肪肉瘤，因在 CT 扫描上偶然发现甲状腺结节而到我们诊所就诊。随后的细针抽吸活检提示为转移性脂肪肉瘤。
患者接受了左甲状腺叶切除术，最终病理证实为 3.3 厘米的 II/III 级转移性黏液样脂肪肉瘤。患者耐受手术情况良好。
我们的病例强调了在评估甲状腺结节时患者病史的作用，以优化准确诊断，因为脂肪肉瘤通常不会转移到甲状腺。我们还提供了所有转移性肉瘤至甲状腺的文献的最新综述。
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