矢状面失衡与成年人抑郁症状：磐城队列研究中的运动障碍综合征与健康结局（LOHAS）。
Sagittal imbalance and symptoms of depression in adults: Locomotive Syndrome and Health Outcomes in the Aizu Cohort Study (LOHAS).
机构信息
Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.
Graduate School of Medicine, Human Health Science, Kyoto University, Kyoto, Japan.
出版信息
Eur Spine J. 2021 Sep;30(9):2450-2456. doi: 10.1007/s00586-020-06660-9. Epub 2020 Nov 22.
PURPOSE
With spinal deformities, mental health can deteriorate due to sagittal imbalance of the spine. The purpose of this study was to clarify the relationship between sagittal imbalance and symptoms of depression among local residents in the community.
METHODS
This study used data from the Locomotive Syndrome and Health Outcomes in Aizu Cohort Study (LOHAS) in 2010. The sagittal vertical axis (SVA) was identified as an indicator of sagittal imbalance. Symptoms of depression were assessed using the 5-item version of the Mental Health Inventory. Participants were classified into three categories based on the SVA balance as normal (< 40 mm), moderate imbalance (40-95 mm), and severe imbalance (> 95 mm). To evaluate the relationship between sagittal imbalance of the spine and symptoms of depression, the adjusted risk ratio (RR) and the 95% confidence interval (CI) were calculated using a generalized linear model with Poisson link.
RESULTS
There were 786 participants included in the statistical analysis. Overall, the mean age was 68.1 y (standard deviation, 8.8 y), and 39.4% were men. The prevalence of symptoms of depression by SVA category was 18.6% for normal, 23.8% for moderate, and 40.6% for severe. On multivariate analysis, the RR of SVA for symptoms of depression compared to the normal category was 1.12 (95% CI 0.7-1.70) for the moderate category and 2.29 (95% CI 1.01-5.17) for the severe category.
CONCLUSION
In local community residents, sagittal imbalance had a significant association with symptoms of depression.
目的
脊柱畸形可导致脊柱矢状失平衡，进而使心理健康恶化。本研究旨在明确脊柱矢状失平衡与社区居民抑郁症状之间的关系。
方法
本研究使用了 2010 年 Locomotive Syndrome and Health Outcomes in Aizu Cohort Study（LOHAS）的数据。矢状垂直轴（SVA）被确定为矢状失平衡的指标。采用心理健康量表的 5 项版本评估抑郁症状。根据 SVA 平衡情况，将参与者分为三组：正常（<40mm）、中度失衡（40-95mm）和重度失衡（>95mm）。采用广义线性模型和泊松链接，计算调整后的风险比（RR）和 95%置信区间（CI），以评估脊柱矢状失平衡与抑郁症状之间的关系。
结果
共纳入 786 名参与者进行统计分析。总体而言，平均年龄为 68.1 岁（标准差 8.8 岁），39.4%为男性。按 SVA 分类，正常组、中度失衡组和重度失衡组抑郁症状的患病率分别为 18.6%、23.8%和 40.6%。多变量分析显示，与正常组相比，中度失衡组和重度失衡组 SVA 与抑郁症状的 RR 分别为 1.12（95%CI 0.7-1.70）和 2.29（95%CI 1.01-5.17）。
结论
在社区居民中，脊柱矢状失平衡与抑郁症状显著相关。
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