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成人脊柱畸形翻修手术的影像学及患者报告结局

Radiographic and patient reported outcomes in adult spinal deformity revision surgery.

作者信息

Erkilinc Mehmet, Fernandez Laviel, Kara Deniz, Jauregui Julio, Ries Tomas, Gupta Munish

机构信息

Department of Orthopedic Surgery, St. Louis University, St. Louis, USA.

St. Louis University, SSM Health Cardinal Glennon Childrens Hospital, 1465 South Grand Blvd, Saint Louis, MO, 63104, USA.

出版信息

Eur Spine J. 2025 May 26. doi: 10.1007/s00586-025-08952-4.

DOI:10.1007/s00586-025-08952-4
PMID:40418228
Abstract

PURPOSE

To determine the differences in radiographic and health-related quality of life outcomes of patients who were either younger or older than 65 years of age and underwent a revision adult spinal deformity surgery.

METHODS

This is a single center study that retrospectively evaluated the functional scores and radiographic parameters in patients who underwent a revision adult spinal deformity surgery between January 2015 and June 2020. Radiographic measurements and HRQOLs were measured pre-operatively, post-operatively and at final follow up. A total of 103 patients met inclusion criteria. These were divided into 2 groups, under 65 years (n = 60 patients), and over 65 years of age (n = 43 patients).

RESULTS

Analysis of the radiographic parameters at the various time points demonstrated statistically significant differences between preoperative and early postoperative parameters, except for thoracic kyphosis TK(p = 0.018). In both group, there was statistically significant improvement in PI-LL difference and LL. Comparison of the early postoperative follow-up data and last follow-up data showed statistically significant difference for PT (p = 0.013), TK (p = 0.012) and SVA (p = 0.015). When analyzing HRQOLs at the various time points, there was a statistically significant improvement in both groups between preoperative and final follow up scores and there was no significant difference between two groups. Complications in patients over 65 years of age occurred in 10/43(23%). In the under 65 group, complications occurred in 16/60 (27%).

CONCLUSION

This study demonstrated similar improvement in radiographic parameters and functional outcome scores in patients undergoing revision ASD surgery stratified according to age.

摘要

目的

确定年龄小于或大于65岁且接受成人脊柱畸形翻修手术的患者在影像学和健康相关生活质量结果方面的差异。

方法

这是一项单中心研究,回顾性评估了2015年1月至2020年6月期间接受成人脊柱畸形翻修手术的患者的功能评分和影像学参数。在术前、术后及末次随访时测量影像学指标和健康相关生活质量。共有103例患者符合纳入标准。这些患者被分为两组,65岁以下(n = 60例患者)和65岁以上(n = 43例患者)。

结果

对不同时间点的影像学参数分析显示,除胸椎后凸角TK外(p = 0.018),术前和术后早期参数之间存在统计学显著差异。在两组中,PI-LL差值和LL均有统计学显著改善。术后早期随访数据与末次随访数据比较,PT(p = 0.013)、TK(p = 0.012)和SVA(p = 0.015)存在统计学显著差异。在分析不同时间点的健康相关生活质量时,两组术前和末次随访评分之间均有统计学显著改善,且两组之间无显著差异。65岁以上患者的并发症发生率为10/43(23%)。在65岁以下组中,并发症发生率为16/60(27%)。

结论

本研究表明,根据年龄分层的接受成人脊柱畸形翻修手术的患者在影像学参数和功能结果评分方面有相似的改善。

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本文引用的文献

1
Clinical Outcomes of Corrective Fusion Surgery From the Thoracic Spine to the Pelvis for Adult Spinal Deformity at 1, 2, and 5 years Postoperatively.术后 1、2、5 年胸腰椎到骨盆矫正融合手术治疗成人脊柱畸形的临床疗效。
Spine (Phila Pa 1976). 2022 Jun 1;47(11):792-799. doi: 10.1097/BRS.0000000000004347. Epub 2022 Feb 22.
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Evaluation of global alignment and proportion score in an independent database.在独立数据库中评估全局比对和比例评分。
Spine J. 2021 Sep;21(9):1549-1558. doi: 10.1016/j.spinee.2021.04.004. Epub 2021 Apr 12.
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Sagittal imbalance and symptoms of depression in adults: Locomotive Syndrome and Health Outcomes in the Aizu Cohort Study (LOHAS).
矢状面失衡与成年人抑郁症状:磐城队列研究中的运动障碍综合征与健康结局(LOHAS)。
Eur Spine J. 2021 Sep;30(9):2450-2456. doi: 10.1007/s00586-020-06660-9. Epub 2020 Nov 22.
4
Are Higher Global Alignment and Proportion Scores Associated With Increased Risks of Mechanical Complications After Adult Spinal Deformity Surgery? An External Validation.全球高对准率和高比例评分与成人脊柱畸形手术后机械并发症风险增加相关吗?一项外部验证。
Clin Orthop Relat Res. 2021 Feb 1;479(2):312-320. doi: 10.1097/CORR.0000000000001521.
5
Prediction of satisfaction after correction surgery for adult spinal deformity: differences between younger and older patients.成人脊柱畸形矫正术后满意度的预测:年轻患者和老年患者的差异。
Eur Spine J. 2020 Dec;29(12):3051-3062. doi: 10.1007/s00586-020-06611-4. Epub 2020 Oct 1.
6
Predictors of Poor Global Alignment and Proportion Score After Surgery for Adult Spinal Deformity.成人脊柱畸形术后整体平衡和比例评分不良的预测因素。
Spine (Phila Pa 1976). 2019 Oct 1;44(19):E1136-E1143. doi: 10.1097/BRS.0000000000003086.
7
Global Alignment and Proportion (GAP) Score: Development and Validation of a New Method of Analyzing Spinopelvic Alignment to Predict Mechanical Complications After Adult Spinal Deformity Surgery.整体对线与比例(GAP)评分:一种分析脊柱骨盆对线以预测成人脊柱畸形手术后机械并发症的新方法的开发与验证
J Bone Joint Surg Am. 2017 Oct 4;99(19):1661-1672. doi: 10.2106/JBJS.16.01594.
8
Clinical Results and Functional Outcomes in Adult Patients After Revision Surgery for Spinal Deformity Correction: Patients Younger than 65 Years Versus 65 Years and Older.成人脊柱畸形矫正翻修手术后的临床结果与功能转归:65岁及以下患者与65岁及以上患者的比较
Spine Deform. 2013 Sep;1(5):371-376. doi: 10.1016/j.jspd.2013.07.003. Epub 2013 Sep 25.
9
Increase in spinal deformity surgery in patients age 60 and older is not associated with increased complications.60岁及以上患者脊柱畸形手术量的增加与并发症增加无关。
Spine J. 2017 May;17(5):627-635. doi: 10.1016/j.spinee.2016.11.005. Epub 2016 Nov 21.
10
Results of Revision Surgery for Proximal Junctional Kyphosis Following Posterior Segmental Instrumentation: Minimum 2-Year Postrevision Follow-Up.后路节段性内固定术后近端交界性后凸翻修手术的结果:至少2年的翻修后随访
Spine (Phila Pa 1976). 2016 Dec 15;41(24):E1444-E1452. doi: 10.1097/BRS.0000000000001664.