School of Optometry and Vision Science, UNSW, Sydney, NSW, 2052, Australia.
Ophthalmic Physiol Opt. 2021 Jan;41(1):105-115. doi: 10.1111/opo.12762. Epub 2020 Nov 22.
Many dry eye questionnaires are available, but these may not be suitable for paediatric eye care. The feasibility of use and repeatability of symptom questionnaires administered to children was examined.
Participants aged 6-15 years (n = 62; 25M:37F; 40% male) completed six questionnaires twice in random order at a single visit: Symptoms assessment in dry eye (SANDE), ocular surface disease index (OSDI), numerical rating scale (NRS), ocular comfort index (OCI, n = 30), dry eye questionnaire 5 (DEQ-5) and the instant ocular symptoms survey (IOSS). Completion time and need for assistance were recorded and relationships with age examined (Pearson correlation, independent t-test). The number of participants requiring assistance and with which items were compared (linear mixed model, pairwise test). Repeatability (coefficient of repeatability (CoR), limit of agreement, bias) and intraclass correlation coefficient (ICC) were examined.
Completion time was ≤2 min for each individual questionnaire. Younger participants took longer to complete (r = -0.43 to -0.60, p ≤ 0.01), and required more assistance (p ≤ 0.001). Forty-eight participants required assistance with at least one questionnaire. Older children (13-15 years) only required assistance with OSDI (p ≤ 0.004) and NRS (p ≤ 0.003). Participants required more assistance with SANDE, OSDI and NRS than with DEQ-5 and IOSS (p ≤ 0.02) and with gritty (OSDI, 77% of participants; OCI, 100%) and foreign body sensation (NRS, 92%) items. CoR was similar for all questionnaires with no evidence of a learning effect (p > 0.05). ICC was moderate to excellent.
Dry eye questionnaires can be used reliably in paediatric eye care; more time and assistance may be required for younger children. The DEQ-5 and IOSS are recommended for use in younger age children.
有许多干眼症问卷可供选择，但这些问卷可能并不适合儿科眼部护理。本研究旨在评估这些问卷在儿童中的使用可行性和重复性。
本研究共纳入 62 名年龄在 6-15 岁的参与者（25 名男性，37 名女性；40%为男性）。在单次就诊时，他们随机两次完成了 6 份问卷：干眼症状评估量表（SANDE）、眼表疾病指数（OSDI）、数字评分量表（NRS）、眼舒适度指数（OCI，n=30）、干眼问卷 5 项（DEQ-5）和即时眼部症状调查（IOSS）。记录完成时间和所需帮助，并分析其与年龄的关系（Pearson 相关分析、独立 t 检验）。比较需要帮助的参与者人数和需要帮助的项目（线性混合模型、两两检验）。评估重复性（可重复性系数（CoR）、一致性界限、偏差）和组内相关系数（ICC）。
每份问卷的完成时间均≤2 分钟。年龄较小的参与者完成时间较长（r=-0.43 至-0.60，p≤0.01），且需要更多帮助（p≤0.001）。48 名参与者至少需要一种问卷的帮助。年龄较大的儿童（13-15 岁）仅在 OSDI（p≤0.004）和 NRS（p≤0.003）问卷中需要帮助。与 DEQ-5 和 IOSS 相比，参与者在 SANDE、OSDI 和 NRS 问卷中需要更多的帮助（p≤0.02），且在有砂砾感（OSDI，77%的参与者；OCI，100%）和异物感（NRS，92%）的项目中需要更多帮助（p≤0.02）。所有问卷的 CoR 相似，且无学习效应的证据（p>0.05）。ICC 为中等至优秀。
干眼症问卷可在儿科眼部护理中可靠使用；年龄较小的儿童可能需要更多的时间和帮助。DEQ-5 和 IOSS 建议用于年龄较小的儿童。
