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年轻女性 1 型糖尿病伴发其他自身免疫性疾病患者的性功能。

Female Sexual Function in Young Women With Type 1 Diabetes and Additional Autoimmune Diseases.

机构信息

Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; Division of Endocrinology and Metabolic Diseases, University of Campania "Luigi Vanvitelli", Naples, Italy.

Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

出版信息

J Sex Med. 2021 Jan;18(1):219-223. doi: 10.1016/j.jsxm.2020.10.006. Epub 2020 Nov 19.

Abstract

BACKGROUND

Female sexual dysfunctions (FSDs) are frequent concerns in women with type 1 diabetes (T1D), which is frequently associated with other autoimmune diseases (ADs).

AIM

To assess sexual function in young type 1 diabetic women with or without additional ADs.

METHODS

Women with T1D aged 18-35 years with a stable couple relationship and no oral contraceptive use were enrolled. Diabetic women with concomitant ADs were also identified. All women completed the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale.

OUTCOMES

The main outcome was the prevalence of FSD. The FSFI-single domain scores were also evaluated in diabetic women with or without additional ADs.

RESULTS

The global population included 154 diabetic women, of whom 66 (42%) had at least one additional AD. The prevalence of FSD was similar among diabetic women with and those without (30% vs 32%, P = .980) additional ADs. The FSFI-desire score was significantly lower among diabetic women with concomitant ADs than those without ADs [median (interquartile range), 4.1 (3.6, 4.8) vs 4.6 (4.0, 5.0), P = .042].

CLINICAL IMPLICATIONS

An early evaluation of sexual function in women with T1D and concomitant ADs should be encouraged.

STRENGTHS & LIMITATIONS: Major strengths are the use of 2 validated tools to diagnose FSD and the relatively large number of subjects investigated. The limitations include the cross-sectional nature of the study, which does not allow to make inference regarding the cause and effect.

CONCLUSION

Diabetic women with additional ADs show an impairment in sexual desire as compared with those suffering only from diabetes. Longo M, Cirillo P, Scappaticcio L, et al. Female Sexual Function in Young Women With Type 1 Diabetes and Additional Autoimmune Diseases. J Sex Med 2021;18:219-223.

摘要

背景

女性性功能障碍(FSD)是 1 型糖尿病(T1D)女性常见的关注点,而 1 型糖尿病常与其他自身免疫性疾病(AD)相关。

目的

评估患有或不患有其他自身免疫性疾病的年轻 1 型糖尿病女性的性功能。

方法

纳入年龄在 18-35 岁之间、稳定伴侣关系且无口服避孕药使用史的 1 型糖尿病女性。还确定了同时患有其他自身免疫性疾病的糖尿病女性。所有女性均完成女性性功能指数(FSFI)和女性性困扰量表的评估。

结果

主要结局是 FSD 的患病率。还评估了患有或不患有其他自身免疫性疾病的糖尿病女性的 FSFI 单项评分。

结论

与仅患有糖尿病的女性相比,患有其他自身免疫性疾病的糖尿病女性的性欲受损。患有其他自身免疫性疾病的糖尿病女性的 FSFI 欲望评分明显低于无其他自身免疫性疾病的糖尿病女性[中位数(四分位距),4.1(3.6,4.8)比 4.6(4.0,5.0),P=0.042]。

意义

应鼓励对患有 T1D 和合并 AD 的女性进行早期性功能评估。

局限性

本研究的主要优势在于使用了 2 种经过验证的工具来诊断 FSD,以及调查了相对较多的研究对象。局限性包括研究的横断面性质,这使得无法对因果关系做出推断。

Longo M、Cirillo P、Scappaticcio L 等人。《年轻 1 型糖尿病合并其他自身免疫性疾病女性的性功能》。J Sex Med 2021;18:219-223。

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