Stechova Katerina, Mastikova Lenka, Urbaniec Krzysztof, Vanis Miroslav, Hylmarova Simona, Kvapil Milan, Pastor Zlatko
Department of Internal Medicine, University Hospital Motol and 2nd Medical Faculty of Charles University, Prague, Czech Republic.
Department of Internal Medicine, University Hospital Motol and 2nd Medical Faculty of Charles University, Prague, Czech Republic; Department of Clinical Hematology, University Hospital Motol and 2nd Medical Faculty of Charles University, Prague, Czech Republic.
Sex Med. 2019 Jun;7(2):217-226. doi: 10.1016/j.esxm.2019.03.001. Epub 2019 Apr 4.
More sexual problems are reported among people treated for diabetes; however, this situation is less explored in women than in men.
To analyze the presence and causal links of female sexual dysfunction (FSD) among Czech women treated for type 1 diabetes.
40 women completed a national version of the Female Sexual Function Index (FSFI), Female Sexual Distress Scale-revised (FSDS-R), and Beck's Depression Inventory-II (BDI-II). A metabolic and endocrine analysis was done using blood samples. Data were statistically analyzed using SPSS v.24 and the R environment.
Patient details (personal information, diabetes-related data, and sex history), sexual performance (the FSFI and FSDS-R scores), and level of depression (the BDI-II score) were measured.
FSD was present in 58% of the participants (based on the FSFI score), and 38% women declared significant sexual distress (according to their FSDS-R score). Even though only 4 women fulfilled the criteria for depression, we observed a strong association between BDI-II and FSFI (for total FSFI score P = .012, ρ = -0.394) resp. FSDS-R scores (P < .001, ρ = 0.552). Although we were not able to establish a clear direct connection between FSD and metabolic control, BDI-II scores were closely correlated with glycosylated hemoglobin (P = .009, ρ = 0.407). The duration of diabetes (based on FSDS-R: P = .046) but neither age nor the presence of chronic diabetic microvascular complications was associated with a higher FSD occurrence. We also observed an association between FSD and the presence of autoimmune hypothyroidism, even when successfully treated (FSDS-R: P = .009; FSFI: P = .067).
FSD is more common in women with type 1 diabetes than in healthy women, and coexisting thyroid autoimmune disease seems to exacerbate FSD. Women suffering from type 1 diabetes, and particularly those with additional endocrinopathies, should be actively screened for FSD. Stechova K, Mastikova L, Urbaniec K, et al. Sexual Dysfunction in Women Treated for Type 1 Diabetes and the Impact of Coexisting Thyroid Disease. Sex Med 2019;7:217-226.
接受糖尿病治疗的人群中报告的性问题更多；然而，女性中的这种情况比男性中研究得更少。
分析接受1型糖尿病治疗的捷克女性中女性性功能障碍（FSD）的存在情况及其因果关系。
40名女性完成了一份全国版的女性性功能指数（FSFI）、修订后的女性性困扰量表（FSDS-R）和贝克抑郁量表第二版（BDI-II）。使用血样进行代谢和内分泌分析。数据使用SPSS v.24和R环境进行统计分析。
测量患者详细信息（个人信息、糖尿病相关数据和性史）、性功能（FSFI和FSDS-R评分）以及抑郁程度（BDI-II评分）。
58%的参与者存在FSD（基于FSFI评分），38%的女性表示有明显的性困扰（根据她们的FSDS-R评分）。尽管只有4名女性符合抑郁标准，但我们观察到BDI-II与FSFI之间存在强关联（对于FSFI总分，P = 0.012，ρ = -0.394），以及BDI-II与FSDS-R评分之间存在强关联（P < 0.001，ρ = 0.552）。尽管我们未能在FSD与代谢控制之间建立明确的直接联系，但BDI-II评分与糖化血红蛋白密切相关（P = 0.009，ρ = 0.407）。糖尿病病程（基于FSDS-R：P = 0.046）与FSD发生率较高相关，但年龄和慢性糖尿病微血管并发症的存在与否均与FSD发生率无关。我们还观察到FSD与自身免疫性甲状腺功能减退的存在之间存在关联，即使在成功治疗后也是如此（FSDS-R：P = 0.009；FSFI：P = 0.067）。
1型糖尿病女性中的FSD比健康女性中更常见，并存的甲状腺自身免疫疾病似乎会加剧FSD。患有1型糖尿病的女性，尤其是那些伴有其他内分泌疾病的女性，应积极筛查FSD。斯特乔娃K、马斯蒂科娃L、乌尔巴涅茨K等。1型糖尿病女性的性功能障碍及并存甲状腺疾病的影响。性医学2019；7：217 - 226。
