巩膜扣带术后孔源性视网膜脱离脉络膜血管变化。

Choroidal vascular changes after encircling scleral buckling for rhegmatogenous retinal detachment.

机构信息

Ophthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

Department of Ophthalmology, University of "Magna Græcia", Catanzaro, Italy.

出版信息

Eye (Lond). 2021 Sep;35(9):2619-2623. doi: 10.1038/s41433-020-01307-x. Epub 2020 Nov 23.

DOI:10.1038/s41433-020-01307-x

PMID:33223533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8376964/

Abstract

BACKGROUND/OBJECTIVES: There is an ongoing debate on whether encircling scleral buckling (SB) procedure for the treatment of rhegmatogenous retinal detachment (RRD) may cause an impairment in choroidal blood flow. The aim of this study was to compare choroidal vascularity index (CVI) and subfoveal choroidal thickness (CT) between eyes that had undergone encircling SB with unoperated fellow eyes (FEs).

SUBJECTS/METHODS: Thirty patients treated with encircling SB for unilateral RRD were included. Demographic and clinical characteristics as well as enhanced depth imaging-optical coherence tomography scans were retrospectively collected. Images were binarised using ImageJ software, total choroidal area along with luminal and stromal area (respectively, TCA, LA and SA) were segmented and the CVI was computed as the ratio of LA/TCA. In addition, CT was evaluated.

RESULTS

The mean follow-up interval between surgery and examination was 25.5 ± 16.8 months. Choroidal thickness, TCA, LA and SA were significantly increased in the operated eyes compared to FEs (respectively, 271.7 ± 78.0 µm vs. 238.5 ± 83.4, P = 0.001; 1.804 ± 0.491 mm vs. 1.616 ± 0.496, P = 0.001; 1.199 ± 0.333 mm vs. 1.067 ± 0.337, P < 0.001 and 0.605 ± 0.171 mm vs. 0.550 ± 0.171, P = 0.001). Conversely, CVI did not significantly differ between the two groups (66.4 ± 3.6 vs. 65.9 ± 3.2, P = 0.490).

CONCLUSIONS

In conclusion, eyes treated with encircling SB for RRD presented increased LA, SA and CT compared with FEs, but showed no difference in CVI.

摘要

背景/目的：关于巩膜环扎术（SB）治疗孔源性视网膜脱离（RRD）是否会导致脉络膜血流受损，目前存在争议。本研究旨在比较接受巩膜环扎术的患眼与未手术对侧眼（FE）的脉络膜血管指数（CVI）和中心凹下脉络膜厚度（CT）。

受试者/方法：本研究纳入了 30 例接受巩膜环扎术治疗单侧 RRD 的患者。回顾性收集了人口统计学和临床特征以及增强深度成像光学相干断层扫描（EDI-OCT）图像。使用 ImageJ 软件对图像进行二值化，分割总脉络膜面积以及管腔和基质面积（分别为 TCA、LA 和 SA），并计算 LA/TCA 的比值作为 CVI。此外，还评估了 CT。

结果

手术与检查之间的平均随访间隔为 25.5±16.8 个月。与 FE 相比，手术眼的脉络膜厚度、TCA、LA 和 SA 均显著增加（分别为 271.7±78.0µm 比 238.5±83.4µm，P=0.001；1.804±0.491mm 比 1.616±0.496mm，P=0.001；1.199±0.333mm 比 1.067±0.337mm，P<0.001 和 0.605±0.171mm 比 0.550±0.171mm，P=0.001）。相反，两组之间的 CVI 无显著差异（66.4±3.6 比 65.9±3.2，P=0.490）。