Hackett G A, Nicolaides K H, Campbell S
Department of Obstetrics and Gynaecology, King's College Hospital Medical School, Denmark Hill, London, UK.
Br J Obstet Gynaecol. 1987 Nov;94(11):1074-7. doi: 10.1111/j.1471-0528.1987.tb02292.x.
Doppler blood flow studies in 41 pregnancies with oligohydramnios in the second trimester found abnormal patterns in all 14 pregnancies with intrauterine growth retardation but in only one of nine pregnancies with premature rupture of the membranes, and one of 10 with fetal renal defects. Mixed patterns were found in a heterogeneous group of fetuses with other malformations or intrauterine infection. Unlike previous reports a diagnosis was achieved in all pregnancies, suggesting that Doppler studies should be an integral part of the antenatal investigation in such pregnancies.
对41例孕中期羊水过少的孕妇进行多普勒血流研究发现，14例宫内生长受限的孕妇均出现异常血流模式，而9例胎膜早破的孕妇中只有1例出现异常，10例胎儿肾缺陷的孕妇中也只有1例出现异常。在一组患有其他畸形或宫内感染的异质性胎儿中发现了混合血流模式。与之前的报道不同，所有这些孕妇均得以确诊，这表明多普勒研究应成为此类孕妇产前检查的一个组成部分。
