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现代实践中旋磨术导致冠状动脉穿孔的发生率及机制。

Incidence and Mechanisms of Coronary Perforations during Rotational Atherectomy in Modern Practice.

机构信息

Ministry of Health and Welfare Taichung Hospital, Taichung, Taiwan.

Division of Interventional Cardiology, Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.

出版信息

J Interv Cardiol. 2020 Nov 10;2020:1894389. doi: 10.1155/2020/1894389. eCollection 2020.

Abstract

OBJECTIVE

Heavy calcifications remain formidable challenges to PCI, even for well-experienced operators. However, rotational atherectomy (RA)-induced coronary perforations (CPs) still could not be obviated. This study was to explore incidence and mechanisms of RA-induced CP in real-world practice. Knowing why CPs occur in RA should help operators avert such mishaps.

METHOD

Patients who received coronary RA from April 2010 to December 2019 with keywords related to perforations were retrieved from database. The procedure details, angiography, and clinical information were reviewed in detail.

RESULTS

A total of 479 RAs were performed with 11 perforations in 10 procedures among 9 patients documented. The incidence of RA-induced CP was 2.1%. The RA vessels were distributed in different territories, including first diagonal branch. Most CPs could be treated conservatively, but prolonged profound shock predisposed to poor outcome. CPs caused by rotawire tip occurred in 18.2% of cases, inappropriately sized burrs in 18.2% of cases, and rotawire damage with subsequent transection and perforation in another 18.2% of cases. A total of 5 (45.5%) perforations were caused by unintended and unnoticed bias cutting into noncalcified plaques (4, 36.4%) or through calcified vessel wall (1, 9.1%). The mechanisms for certain CPs were unique and illustrated in diagrams.

CONCLUSION

CPs due to RA occur in certain percentage of patients. The mechanisms for CPs are diverse. Wire damage with subsequent transection could occur due to inappropriately repetitive burr stress on the wire body. A significant portion was due to unintended and unnoticed bias cutting into noncalcified plaque or through calcified vessel wall.

摘要

目的

即使对于经验丰富的术者,重度钙化仍然是 PCI 的巨大挑战。然而,旋磨术(RA)引起的冠状动脉穿孔(CP)仍无法避免。本研究旨在探讨真实世界中 RA 引起 CP 的发生率和机制。了解 CP 为何发生在 RA 中,应该有助于术者避免此类并发症。

方法

从数据库中检索了 2010 年 4 月至 2019 年 12 月期间接受冠状动脉 RA 治疗且关键词与穿孔相关的患者。详细回顾了手术过程、血管造影和临床信息。

结果

共进行了 479 例 RA,其中 9 例患者的 10 个手术中记录到 11 例 CP,发生率为 2.1%。RA 血管分布于不同的区域,包括第一对角支。大多数 CP 可保守治疗,但长时间深度休克易导致不良结局。CP 发生的原因包括:旋磨头尖端引起的 CP 占 18.2%,磨头尺寸不合适的占 18.2%,旋磨头损坏继而发生切割和穿孔的占 18.2%。5 例(45.5%)CP 是由于无意且未被注意到的偏心力切割非钙化斑块(4 例,36.4%)或通过钙化的血管壁(1 例,9.1%)引起的。某些 CP 的机制是独特的,并以图表形式展示。

结论

RA 引起的 CP 在一定比例的患者中发生。CP 的机制多种多样。由于对旋磨头施加了不当的重复磨头压力,可能导致旋磨头损坏继而发生切割和穿孔。相当一部分 CP 是由于无意且未被注意到的偏心力切割非钙化斑块或通过钙化的血管壁引起的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ddb/7673942/e6e78b369020/JITC2020-1894389.002.jpg

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