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输尿管支架置入术对女性性功能的影响:一项前瞻性队列研究。

The Effect of Ureteric Stenting on Female Sexual Function: A Prospective Cohort Study.

作者信息

Kazmi Zehra, Umer Daniya, Ather M Hammad

机构信息

Urology, The Aga Khan University, Karachi, PAK.

Surgery, The Aga Khan University, Karachi, PAK.

出版信息

Cureus. 2020 Oct 21;12(10):e11075. doi: 10.7759/cureus.11075.

Abstract

Background and objective Urolithiasis is a highly prevalent disease worldwide, with Pakistan belonging to the stone belt of Asia. The usage of the double J (DJ) stent is highly effective when it comes to the management of urolithiasis. However, studies investigating the side effects of DJ stent placement on sexual function in individuals are scarce. In this study, we aimed to assess the impact of DJ stent placement on sexual function in women. Methods After obtaining ethical approval, a prospective study was conducted at a university hospital from June 2018 to September 2019. All sexually active women requiring semi-rigid ureteroscopy (URS) or flexible URS [retrograde intrarenal surgery (RIRS)] were enrolled. Women with DJ stent placement (Group A) were compared to women who did not require DJ stent (Group B). The outcome variable was to assess temporary sexual dysfunction after DJ stent placement using the standardized Female Sexual Functionality Index (FSFI) in English or its validated vernacular version. The FSFI was completed at four weeks, and again at three months, following URS/RIRS. Results Of the 106 sexually active women initially included in the study, 69 were found to be eligible for final analysis. In Group A, the mean FSFI score at the initial presentation was 31.54 ±4.37. The mean FSFI score at four weeks was lower compared to the baseline score (0 time): 13.96 ±5.5 (p<0.05). At three months, the mean FSFI score returned to near baseline at 32.053 ±5.35 with no significant difference (p=0.65). In comparison to women in Group B, the mean FSFI score at four weeks was significantly lower in Group A (28.87 ±6.59 vs. 13.96 ±5.49; p<0.05). However, there was no significant difference between the mean FSFI scores at any of the three time points within Group B. Conclusion DJ stent insertion results in transient postoperative sexual dysfunction in women, which resolves spontaneously within a span of three months after stent removal.

摘要

背景与目的

尿石症在全球范围内是一种高度流行的疾病,巴基斯坦属于亚洲的结石高发区。双J(DJ)支架在尿石症的治疗中非常有效。然而,关于DJ支架置入对个体性功能副作用的研究很少。在本研究中,我们旨在评估DJ支架置入对女性性功能的影响。方法:在获得伦理批准后,于2018年6月至2019年9月在一家大学医院进行了一项前瞻性研究。纳入所有需要半硬性输尿管镜检查(URS)或软性URS[逆行肾内手术(RIRS)]的性活跃女性。将置入DJ支架的女性(A组)与不需要DJ支架的女性(B组)进行比较。结局变量是使用标准化的英文女性性功能指数(FSFI)或其经过验证的本地语言版本来评估DJ支架置入后的暂时性性功能障碍。FSFI在URS/RIRS术后四周和三个月时完成。结果:最初纳入研究的106名性活跃女性中,69名被认为符合最终分析条件。A组初次就诊时的平均FSFI评分为31.54±4.37。四周时的平均FSFI评分低于基线评分(0时间):13.96±5.5(p<0.05)。三个月时,平均FSFI评分恢复到接近基线水平,为32.053±5.35,无显著差异(p=0.65)。与B组女性相比,A组四周时的平均FSFI评分显著更低(28.87±6.59 vs.13.96±5.49;p<0.05)。然而,B组在三个时间点中的任何一个时间点的平均FSFI评分之间均无显著差异。结论:DJ支架置入导致女性术后出现短暂性性功能障碍,在支架取出后三个月内可自行缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d22d/7678765/36915843a971/cureus-0012-00000011075-i01.jpg

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