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全球结石病的流行病学。

Epidemiology of stone disease across the world.

机构信息

Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

Department of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, Greece.

出版信息

World J Urol. 2017 Sep;35(9):1301-1320. doi: 10.1007/s00345-017-2008-6. Epub 2017 Feb 17.

Abstract

Nephrolithiasis is a highly prevalent disease worldwide with rates ranging from 7 to 13% in North America, 5-9% in Europe, and 1-5% in Asia. Due to high rates of new and recurrent stones, management of stones is expensive and the disease has a high level of acute and chronic morbidity. The goal of this study is to review the epidemiology of stone disease in order to improve patient care. A review of the literature was conducted through a search on Pubmed, Medline, and Google Scholar. This review was presented and peer-reviewed at the 3rd International Consultation on Stone Disease during the 2014 Société Internationale d'Urologie Congress in Glasgow. It represents an update of the 2008 consensus document based on expert opinion of the most relevant studies. There has been a rising incidence in stone disease throughout the world with a narrowing of the gender gap. Increased stone prevalence has been attributed to population growth and increases in obesity and diabetes. General dietary recommendations of increased fluid, decreased salt, and moderate intake of protein have not changed. However, specific recommended values have either changed or are more frequently reported. Geography and environment influenced the likelihood of stone disease and more information is needed regarding stone disease in a large portion of the world including Asia and Africa. Randomized controlled studies are lacking but are necessary to improve recommendations regarding diet and fluid intake. Understanding the impact of associated conditions that are rapidly increasing will improve the prevention of stone disease.

摘要

肾结石是一种在全球范围内普遍存在的疾病,北美的发病率为 7%至 13%,欧洲为 5%至 9%,亚洲为 1%至 5%。由于新结石和复发性结石的发生率较高,结石的治疗费用昂贵,而且该疾病具有较高的急性和慢性发病率。本研究的目的是回顾结石病的流行病学,以改善患者的治疗效果。通过在 Pubmed、Medline 和 Google Scholar 上进行文献检索,对文献进行了回顾。该综述在 2014 年格拉斯哥国际结石病会议期间的第 3 届国际结石病咨询会上进行了陈述和同行评议。它是基于最相关研究的专家意见对 2008 年共识文件的更新。全世界的结石病发病率呈上升趋势,男女差距逐渐缩小。结石病发病率的增加归因于人口增长以及肥胖症和糖尿病发病率的增加。增加液体摄入、减少盐摄入和适度摄入蛋白质的一般饮食建议没有改变。然而,具体的推荐值已经发生了变化或更频繁地被报道。地理和环境影响结石病的发生概率,需要更多关于亚洲和非洲等世界大部分地区结石病的信息。目前缺乏随机对照研究,但这些研究对于改善饮食和液体摄入的建议是必要的。了解迅速增加的相关疾病的影响将有助于预防结石病。

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