磁共振成像引导聚焦超声手术在非侵入性乳腺癌治疗中的创新应用：两例报告
Innovative use of magnetic resonance imaging-guided focused ultrasound surgery for non-invasive breast cancer: a report of two cases.
作者信息
Matsutani Akiko, Ide Yoshimi, Miura Sakiko, Takimoto Masafumi, Amano Sadao, Nakamura Seigo
机构信息
Division of Breast Surgical Oncology, Department of Surgery, Showa University School of Medicine, 1-5-8 Hatanodai Shinagawa-ku, Tokyo, Japan.
Division of Breast Surgical Oncology, Shinntoshinn Musashino Clinic, 2-389-1 Kitabukurocho Omiya-ku, Saitama, Japan.
出版信息
Surg Case Rep. 2020 Nov 23;6(1):294. doi: 10.1186/s40792-020-01032-3.
OBJECTIVE
This report describes the first clinical experience with magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) using the ExAblate 2100 system for non-invasive breast cancer.
METHODS
Two women with non-invasive breast cancer underwent MRgFUS treatment. One week after the MRgFUS treatment, US-guided vacuum-assisted biopsy was performed for the ablated lesions at the same time as breast-conserving surgery.
RESULTS
The patients experienced good cosmetic outcomes and did not experience any severe adverse events, such as skin burns. Pathological examination of the surgical specimens revealed a few degenerated intraductal lesions around the breast biopsy markers.
CONCLUSION
Performing MRgFUS with the new ExAblate 2100 system appears to be safe and feasible. The histopathological results revealed that adequate ultrasound energy in the appropriate location can induce tumor necrosis.
目的
本报告描述了使用ExAblate 2100系统进行磁共振成像引导聚焦超声手术（MRgFUS）治疗非侵入性乳腺癌的首例临床经验。
方法
两名非侵入性乳腺癌女性接受了MRgFUS治疗。MRgFUS治疗一周后，在保乳手术的同时，对消融病灶进行超声引导下真空辅助活检。
结果
患者获得了良好的美容效果，未出现任何严重不良事件，如皮肤烧伤。手术标本的病理检查显示，乳腺活检标记物周围有一些退化的导管内病变。
结论
使用新型ExAblate 2100系统进行MRgFUS似乎是安全可行的。组织病理学结果显示，在适当位置给予足够的超声能量可诱导肿瘤坏死。
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