Mutluer Ferit Onur, Bowen Daniel J, van Grootel Roderick W J, Roos-Hesselink Jolien W, Van den Bosch Annemien E
Department of Cardiology, Erasmus University Medical Center, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.
Department of Cardiology, Erasmus University Medical Center, Room Rg-433,'s-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.
Int J Cardiovasc Imaging. 2021 Apr;37(4):1189-1201. doi: 10.1007/s10554-020-02100-3. Epub 2020 Nov 23.
Three dimensional speckle tracking echocardiography (3D-STE) is a novel modality for the assessment of left ventricular strain (LVS). The aim of our study is to provide single vendor normative strain values measured with 3D-STE in healthy adult caucasians. One hundred fifty-five healthy subjects aged 20 to 72 years (≥ 28 subjects per decile) were prospectively included and examined with 2D and 3D transthoracic echocardiography. In 105 both 3D and 2D-STE were feasible (71%, mean age 44 ± 14 years, 51% female). Mean 3D tangential strain (3D-TS) was - 32 ± 2.9%. 3D global longitudinal strain (3D-GLS) demonstrated a significant but not very strong correlation with 2D-GLS values (- 19.7 ± 1.8% vs - 20.4 ± 2.2%, r = 0.462, p < 0.001). No gender difference was observed in 3D strain parameters. 3D-GLS decreased with increasing age stratum (p = 0.024). LVEF was associated with 3D-TS and 3D-GLS (r = - 0.819, p ≤ 0.001 for 3D-TS, p = - 0.477, r < 0.001, p = 0.001 for 3D-GLS). In this single vendor study age and gender-specific normative LV 3D-TS values were reported for healthy adult caucasians. In a significant proportion of the subjects 3D-STE was not feasible, but when feasible, 3D-STE shows excellent association with LVEF, and is therefore a promising novel modality for the assessment of the myocardial function, provided that issues of limited feasibility and temporal resolution are addressed.
三维斑点追踪超声心动图（3D-STE）是一种评估左心室应变（LVS）的新型方法。我们研究的目的是提供在健康成年白种人中使用3D-STE测量的单一供应商标准应变值。前瞻性纳入了155名年龄在20至72岁之间的健康受试者（每个十分位数≥28名受试者），并使用二维和三维经胸超声心动图进行检查。105名受试者的三维和二维STE均可行（71%，平均年龄44±14岁，51%为女性）。平均三维切线应变（3D-TS）为-32±2.9%。三维整体纵向应变（3D-GLS）与二维GLS值呈显著但不太强的相关性（-19.7±1.8%对-20.4±2.2%，r=0.462，p<0.001）。在三维应变参数中未观察到性别差异。3D-GLS随年龄层增加而降低（p=0.024）。左心室射血分数（LVEF）与3D-TS和3D-GLS相关（3D-TS的r=-0.819，p≤0.001；3D-GLS的r=-0.477，p<0.001，p=0.001）。在这项单一供应商研究中，报告了健康成年白种人的年龄和性别特异性左心室3D-TS标准值。在相当一部分受试者中，3D-STE不可行，但当可行时，3D-STE与LVEF显示出良好的相关性，因此，只要解决有限可行性和时间分辨率问题，它就是一种有前景的评估心肌功能的新型方法。
