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一例超长病毒脱落期病例:细胞培养物能否成为推动 COVID-19 患者出院的诊断工具?

A case of extremely prolonged viral shedding: Could cell cultures be a diagnostic tool to drive COVID-19 patient discharge?

机构信息

Laboratory of Clinical Microbiology, Virology and Bioemergencies, ASST Fatebenefratelli Sacco, Milan, Italy.

Department of Infectious Diseases, ASST Fatebenefratelli Sacco, Milan, Italy.

出版信息

Int J Infect Dis. 2021 Mar;104:631-633. doi: 10.1016/j.ijid.2020.11.161. Epub 2020 Nov 20.

Abstract

This study addressed the case of a patient with prolonged COVID-19 viral shedding, reported by Real-Time PCR, until 71 days from symptom onset. However, viral culture received negative results after 30 days from symptom onset. Therefore, viral culture may be a worthwhile test for patients requiring discharge, in particular for those presenting prolonged viral shedding.

摘要

本研究报告了一例 COVID-19 病毒延长脱落的患者,经实时 PCR 检测,从症状出现起 71 天仍持续阳性。然而,从症状出现起 30 天后病毒培养结果为阴性。因此,对于需要出院的患者,特别是那些病毒持续脱落时间较长的患者,病毒培养可能是一项有价值的检测。

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