2012-2018 年英格兰对可能的中东呼吸综合征冠状病毒病例的检测和调查六年经验。
Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018.
机构信息
National Infection Service, Public Health England, 61 Colindale Avenue, London, NW9 5EQ, UK.
National Infection Service, Public Health England, 61 Colindale Avenue, London, NW9 5EQ, UK.
出版信息
Public Health. 2020 Dec;189:141-143. doi: 10.1016/j.puhe.2020.10.007. Epub 2020 Oct 20.
OBJECTIVES
Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018.
STUDY DESIGN
This was a descriptive study using surveillance data.
METHODS
Local health protection teams in England report possible MERS cases to the National Infection Service with clinical and laboratory data.
RESULTS
A total of 1301 possible MERS cases were identified in the study period. Five cases were laboratory-confirmed MERS. The majority of cases had travelled to Saudi Arabia (56.7%) and United Arab Emirates (25.9%). Fifty-four percent of cases were men and 43.7% were women. The majority of cases (65.1%) were aged 45 years or older. The number of tests increased in the period after Hajj each year. Laboratory-confirmed alternative diagnoses were available for 513 (39.4%) cases; influenza was the most common virus detected (n = 255, 52.4%).
CONCLUSIONS
Our study highlights the importance of differential diagnosis of influenza and other respiratory pathogens and early influenza antiviral treatment.
目的
自 2012 年 9 月以来，英国一直在对中东呼吸综合征（MERS）进行监测。本研究描述了 2012 年至 2018 年期间在英格兰的监测结果。
研究设计
这是一项使用监测数据的描述性研究。
方法
英格兰当地卫生保护小组向国家传染病服务机构报告可能的 MERS 病例，并提供临床和实验室数据。
结果
在研究期间共发现 1301 例可能的 MERS 病例。5 例实验室确诊为 MERS。大多数病例曾前往沙特阿拉伯（56.7%）和阿拉伯联合酋长国（25.9%）。54%的病例为男性，43.7%为女性。大多数病例（65.1%）年龄在 45 岁或以上。每年朝觐后，检测数量增加。513 例（39.4%）病例有实验室确诊的其他诊断；流感是检测到的最常见病毒（n=255，52.4%）。
结论
我们的研究强调了流感和其他呼吸道病原体的鉴别诊断以及早期流感抗病毒治疗的重要性。
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