探索肿瘤亚克隆的生态进化动力学
Exploring the Eco-Evolutionary Dynamics of Tumor Subclones.
作者信息
Rampias Theodoros
机构信息
Biomedical Research Foundation of the Academy of Athens, Basic Research Center, 11527 Athens, Greece.
出版信息
Cancers (Basel). 2020 Nov 19;12(11):3436. doi: 10.3390/cancers12113436.
Abstract
Mutational processes constantly shape the cancer genome and defects in DNA repair pathways of tumor cells facilitate the accumulation of genomic alterations [...].
摘要
突变过程不断塑造癌症基因组，肿瘤细胞DNA修复途径中的缺陷促进了基因组改变的积累[……]。
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