Suppr超能文献

双绒毛膜三羊膜囊三胎妊娠的围产期结局

[Perinatal outcomes of dichorionic triamniotic triplet pregnancy].

作者信息

Zhou Y, Jiao Y J, Wei Y, Yuan P B, Wang X J, Zhao Y Y

机构信息

Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.

Department of Obstetrics, Tongzhou District Maternal and Child Health Hospital, Beijing 101100, China.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 2020 Nov 25;55(11):764-769. doi: 10.3760/cma.j.cn112141-20200422-00346.

Abstract

To analyze the perinatal outcomes in different methods of multifetal pregnancy reduction in dichorionic triamniotic (DCTA) triplet pregnancy. A retrospective analysis was performed on 57 cases of DCTA triplets in Peking University Third Hospital from January 1, 2010 to January 1, 2020, including 27 cases in expectant pregnancy group and 30 cases in selective fetal reduction (FR) group. The selective FR group was further divided into 3 subgroups according to different FR methods:retaining monochorionic dichorionic (MCDA) group, retaining dichorionic dichorionic (DCDA) group, and retaining singleton group. The perinatal outcomes of expectant pregnancy group and 3 subgroups of selective FR group were compared. The gestational weeks in selective FR group was (34.5±5.7) weeks, and full-term delivery rate was 53% (16/30), respectively higher than those of the expectant pregnancy group (29.9±6.0) weeks and 7% (2/27). The miscarriage rate of the selective FR group was 10% (3/30), lower than that of the expectant pregnancy group (33%, 9/27). The differences between the two groups were statistically significant (all <0.05). The ratios of pregnancy complications and newborn admission to neonatal ICU (NICU) in the selective FR group were lower than those of the expectant pregnancy group (all <0.05). In the selective FR group, the gestational weeks in retaining MCDA group (6 cases), retaining DCDA group (13 cases), and retaining singleton group (11 cases) were (32.2±4.3), (33.0±6.3), and (37.4±4.7) weeks; the miscarriage rates were 1/6, 1/13, and 1/11; the premature delivery rates were 4/6, 7/13, and 0/11; the full-term delivery rates were 1/6, 5/13, and 10/11; pregnancies with at least 1 survivor rates were 5/6, 12/13, and 10/11; NICU occupancy rates were 6/8, 9/18 and 0/10, respectively. The retaining singleton group had the highest rate of full-term delivery and the lowest rate of NICU occupancy. Compared with other groups, the differences were statistically significant (all <0.05). The full-term delivery rate was significantly higher in the retaining DCDA group than that of the expectant pregnancy group (<0.05). The risk of DCTA triplet pregnancy is high. Reduction of the MCDA pair to singleton has the highest rate of full-term delivery and the lowest rate of NICU occupancy. For pregnant women who wish to retain twin pregnancy, the risk should be fully informed, and consider reduction of one fetus of the MCDA and retaining DCDA twins to continue pregnancy.

摘要

分析双绒毛膜三羊膜囊(DCTA)三胎妊娠不同减胎方法的围产期结局。对2010年1月1日至2020年1月1日北京大学第三医院收治的57例DCTA三胎妊娠病例进行回顾性分析,其中期待妊娠组27例,选择性减胎(FR)组30例。选择性FR组根据不同减胎方法进一步分为3个亚组:保留单绒毛膜双羊膜囊(MCDA)组、保留双绒毛膜双羊膜囊(DCDA)组和保留单胎组。比较期待妊娠组和选择性FR组3个亚组的围产期结局。选择性FR组的孕周为(34.5±5.7)周,足月分娩率为53%(16/30),分别高于期待妊娠组的(29.9±6.0)周和7%(2/27)。选择性FR组的流产率为10%(3/30),低于期待妊娠组(33%,9/27)。两组差异有统计学意义(均<0.05)。选择性FR组的妊娠并发症发生率和新生儿入住新生儿重症监护病房(NICU)的比例均低于期待妊娠组(均<0.05)。在选择性FR组中,保留MCDA组(6例)、保留DCDA组(13例)和保留单胎组(11例)的孕周分别为(32.2±4.3)、(33.0±6.3)和(37.4±4.7)周;流产率分别为1/6、1/13和1/11;早产率分别为4/6、7/13和0/11;足月分娩率分别为1/6、5/13和10/11;至少有1例存活胎儿的妊娠率分别为5/6、12/13和10/11;NICU入住率分别为6/8、9/18和0/10。保留单胎组的足月分娩率最高,NICU入住率最低。与其他组相比,差异有统计学意义(均<0.05)。保留DCDA组的足月分娩率显著高于期待妊娠组(<0.05)。DCTA三胎妊娠风险高。将MCDA双胎减为单胎的足月分娩率最高,NICU入住率最低。对于希望保留双胎妊娠的孕妇,应充分告知其风险,并考虑将MCDA双胎中的一胎减胎,保留DCDA双胎继续妊娠。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验