多基因序列分型方法分析 2009 年至 2018 年中国宁夏回族自治区牛支原体的遗传多样性。
Multi-locus sequence typing of Mycoplasma bovis to assess its genetic diversity from 2009 to 2018 in Ningxia Hui Autonomous Region, China.
机构信息
Department of Veterinary Clinical Sciences, School of Agriculture, Ningxia University, 750021, Yinchuan, Ningxia, China.
Technology Center Department, Yinchuan Customs, 750000, Yinchuan, Ningxia, China.
出版信息
BMC Vet Res. 2020 Nov 23;16(1):454. doi: 10.1186/s12917-020-02668-x.
BACKGROUND
Mycoplasma bovis (M. bovis) is a highly contagious cattle pathogen spreading worldwide and especially in Ningxia Hui Autonomous Region in China.
RESULTS
Two types of ST, ST10and ST134, were identified in Ningxia Hui Autonomous Region. Thirty-seven strains belonged to ST10 and 28 strains belonged to ST134. ST134 was a new ST and first found in 2009 and was only widely distributed in Ningxia Hui Autonomous Region at present. The M. bovis ST10 was widely spread in many provinces in China and was widespread in Ningxia Hui Autonomous Region since 2010. It is speculated that the prevalence of M. bovis ST10 in Ningxia Hui Autonomous Region began in 2010.
CONCLUSIONS
This study is the first report on the genetic diversity of M. bovis from 2009 to 2018 in Ningxia Hui Autonomous Region and provides the epidemiological information. These results may help further our understanding of the evolution of M. bovis and provide information that may be useful for the development of novel vaccines.
背景
牛支原体（M. bovis）是一种高度传染性的牛病原体，在全球范围内传播，尤其是在中国宁夏回族自治区。
结果
在宁夏回族自治区鉴定出两种 ST，ST10 和 ST134。37 株属于 ST10，28 株属于 ST134。ST134 是一种新的 ST，于 2009 年首次发现，目前仅广泛分布于宁夏回族自治区。M. bovis ST10 在中国许多省份广泛传播，自 2010 年以来在宁夏回族自治区广泛传播。据推测，宁夏回族自治区 M. bovis ST10 的流行始于 2010 年。
结论
本研究首次报道了 2009 年至 2018 年宁夏回族自治区 M. bovis 的遗传多样性，提供了流行病学信息。这些结果可能有助于进一步了解 M. bovis 的进化，并为新型疫苗的开发提供有用的信息。
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