33 项轻躁狂清单（HCL-33）在筛查双相障碍青少年中的验证。
Validation of the 33-item Hypomania Checklist (HCL-33) in screening adolescents with bipolar disorder.
机构信息
Department of Psychiatry, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Unit of Psychiatry, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China; Center for Cognition and Brain Sciences, University of Macau, Macao SAR, China; Institute of Advanced Studies in Humanities and Social Sciences, University of Macau, Macao SAR, China.
出版信息
J Affect Disord. 2021 Feb 15;281:786-791. doi: 10.1016/j.jad.2020.11.062. Epub 2020 Nov 12.
BACKGROUND
Adolescents with bipolar disorder (BD) are often misdiagnosed with major depressive disorder (MDD), which delays the introduction of appropriate treatment resulting in adverse outcomes. This study examined the psychometric properties of the 33-item Hypomania Checklist (HCL-33) and its accuracy to distinguish BD from MDD in adolescents.
METHOD
A total of 248 participants (171 MDD and 77 BD patients) were recruited from a university-affiliated hospital in China. Depression was measured with the Hamilton Depression Rating Scale. All participants completed the assessment with the HCL-33.
RESULTS
A two-factor structure was found for the HCL-33, which explained 30.2% of the total variance. The internal consistency and split half reliability of the total scale were acceptable. The optimal cut-off value of 18 generated sensitivity of 0.52 and specificity of 0.73 for distinguishing BD from MDD.
CONCLUSION
The HCL-33 seems to be a useful screening instrument to distinguish BD from depressed adolescents. However, considering certain less than robust psychometric properties, the HCL-33 needs to be modified and further refined for adolescent patients.
背景
双相情感障碍（BD）青少年常被误诊为重度抑郁症（MDD），这会延迟引入适当的治疗，导致不良后果。本研究旨在检验 33 项轻躁狂清单（HCL-33）的心理测量特性及其在青少年中区分 BD 和 MDD 的准确性。
方法
共招募了 248 名参与者（171 名 MDD 和 77 名 BD 患者），他们来自中国一家大学附属医院。抑郁程度用汉密尔顿抑郁评定量表（Hamilton Depression Rating Scale）进行测量。所有参与者均完成 HCL-33 的评估。
结果
HCL-33 存在两因素结构，解释了总方差的 30.2%。总量表的内部一致性和半分信度可接受。18 分的最佳截断值对区分 BD 和 MDD 的敏感性为 0.52，特异性为 0.73。
结论
HCL-33 似乎是一种有用的筛查工具，可用于区分 BD 和抑郁青少年。然而，考虑到某些不太理想的心理测量特性，HCL-33 需要进一步修改和细化，以适用于青少年患者。
Zotero 插件