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肠道病毒感染导致早产儿坏死性小肠结肠炎。

Parechovirus infection as a cause of necrotising enterocolitis in a premature neonate.

机构信息

Neonatology, Sunshine Hospital, Saint Albans, Victoria, Australia.

Neonatology, Sunshine Hospital, Saint Albans, Victoria, Australia

出版信息

BMJ Case Rep. 2020 Nov 23;13(11):e236872. doi: 10.1136/bcr-2020-236872.

Abstract

Parechovirus is becoming increasingly recognised as a cause of morbidity in the neonatal population. It is widely known to cause sepsis, encephalitis and myocarditis. We report a case of parechovirus as a possible cause of necrotising enterocolitis in a premature neonate. The infant, who was born at 28 weeks' gestation, deteriorated at 1 month of life with fever and abdominal distension and had evidence of intramural bowel gas on imaging. Parechovirus was subsequently isolated from naso-oropharyngeal and rectal swabs, and he was managed medically with antibiotics and cessation of enteral feeds.

摘要

parechovirus 正逐渐被认为是新生儿发病的一个原因。它被广泛认为会导致败血症、脑炎和心肌炎。我们报告了一例 parechovirus 可能导致早产儿坏死性小肠结肠炎的病例。该婴儿胎龄 28 周时出生,1 个月大时出现发热和腹胀,影像学检查显示肠壁内有气体。随后从鼻咽和直肠拭子中分离出 parechovirus,他接受了抗生素和停止肠内喂养的药物治疗。

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本文引用的文献

1
Necrotizing Enterocolitis in Moderate Preterm Infants.中早产儿坏死性小肠结肠炎。
Biomed Res Int. 2018 Oct 10;2018:4126245. doi: 10.1155/2018/4126245. eCollection 2018.
3
Enterovirus and parechovirus infection in children: a brief overview.儿童肠道病毒和细小病毒感染:简要概述
Eur J Pediatr. 2016 Aug;175(8):1023-9. doi: 10.1007/s00431-016-2725-7. Epub 2016 May 7.
4
Severe human parechovirus sepsis beyond the neonatal period.严重人类肠道病毒败血症超出新生儿期。
J Clin Virol. 2011 May;51(1):73-4. doi: 10.1016/j.jcv.2011.02.009. Epub 2011 Mar 8.
7
Necrotising enterocolitis.坏死性小肠结肠炎
Lancet. 2006 Oct 7;368(9543):1271-83. doi: 10.1016/S0140-6736(06)69525-1.
8
Human parechovirus 3 and neonatal infections.人肠道病毒3型与新生儿感染
Emerg Infect Dis. 2005 Jan;11(1):103-5. doi: 10.3201/eid1101.040606.
10
Human parechoviruses--biology and clinical significance.人细小病毒——生物学特性及临床意义
Rev Med Virol. 2000 Jan-Feb;10(1):57-69. doi: 10.1002/(sici)1099-1654(200001/02)10:1<57::aid-rmv266>3.0.co;2-h.

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