Kitazaki Yuki, Asano Rei, Hayashi Kouji, Yamamura Osamu, Tanabe Sawaka, Hamano Tadanori
Department of Neurology, University of Fukui Hospital.
Department of Rehabilitation, Faculty of Health Science, Fukui Health Science University.
Rinsho Shinkeigaku. 2020 Dec 26;60(12):874-877. doi: 10.5692/clinicalneurol.cn-001474. Epub 2020 Nov 20.
A 56-year-old man presented to our hospital as he presented progressive hemiplegia of the right upper limb with no other symptoms, including chest pain. Inter-arm blood pressure difference was not observed. Laboratory investigations revealed an elevated D-dimer value (2.4 μg/ml). Chest X-ray study showed normal findings without widened mediastinum. Brain MRI showed acute multiple brain infarcts in the left posterior limb of the internal capsule and right pons on diffusion-weighted imaging. Bilateral internal carotid arteries were non-occlusive in MRA. Carotid duplex ultrasonography revealed normal internal carotid artery flow velocities bilaterally. Because ischemic lesions were found in multiple vascular territories, and D-dimer value was elevated, the patient underwent thoracic contrast-enhanced-CT to exclude malignant tumors. Stanford type A aortic dissection limited to the ascending aorta was detected. As the plaque had accumulated in the false lumen, we suspected that plaque in the false lumen could be an embolic source. After ascending aortic replacement surgery, brain infarction did not recur during hospitalization. In cases of ischemic stroke wherein multiple vascular territories are detected, and D-dimer value is elevated, even in patients without chest pain, the possibility of painless Stanford type A aortic dissection should be ruled out as an embolic source.
一名56岁男性因右上肢进行性偏瘫就诊于我院,无其他症状,包括胸痛。未观察到双臂血压差异。实验室检查显示D - 二聚体值升高(2.4μg/ml)。胸部X线检查结果正常,纵隔无增宽。脑部MRI在扩散加权成像上显示左侧内囊后肢和右侧脑桥有急性多发性脑梗死。MRA显示双侧颈内动脉无闭塞。颈动脉双功超声检查显示双侧颈内动脉血流速度正常。由于在多个血管区域发现缺血性病变,且D - 二聚体值升高,患者接受了胸部增强CT检查以排除恶性肿瘤。检测到局限于升主动脉的A型主动脉夹层。由于斑块积聚在假腔中,我们怀疑假腔中的斑块可能是栓子来源。升主动脉置换手术后,住院期间脑梗死未复发。在检测到多个血管区域且D - 二聚体值升高的缺血性卒中病例中,即使没有胸痛的患者,也应排除无痛性A型主动脉夹层作为栓子来源的可能性。