曲马多相关性双侧囊样黄斑水肿。

TRAMADOL-ASSOCIATED BILATERAL CYSTOID MACULAR EDEMA.

机构信息

Department of Ophthalmology, Creteil Intercity Hospital, University Paris Est Creteil, Creteil, France ; and.

Department of Ophthalmology, Hospital of the Eastern Paris Region: Coulommiers, Creteil, France .

出版信息

Retin Cases Brief Rep. 2023 Jan 1;17(1):5-8. doi: 10.1097/ICB.0000000000001095.

DOI:10.1097/ICB.0000000000001095

PMID:33229917

Abstract

PURPOSE

To describe a case of bilateral cystoid macular edema in a patient with long-standing tramadol hydrochloride use.

METHODS

Observational case report.

RESULTS

A 73-year-old female patient was referred for progressive, bilateral decreased visual acuity. The patient was phakic with a best-corrected visual acuity at presentation was 20/50 on the right eye and 20/64 on the left eye. The patient had a history of low back pain and had been on tramadol hydrochloride 200 mg/day for 16 years. Bilateral cystoid macular edema was confirmed by means of multimodal imaging, including optical coherence tomography angiography. Tramadol intake was progressively reduced over one month and then completely interrupted. At 3 months follow-up, the cystoid macular edema had completely resolved and the best-corrected visual acuity improved in both eyes.

CONCLUSION

Cystoid macular edema may be associated with longstanding treatment with tramadol hydrochloride. Tramadol hydrochloride-associated cystoid macular edema is described and its resolution on tramadol cessation.

摘要

目的

描述 1 例长期使用盐酸曲马多的患者出现双侧囊样黄斑水肿。

方法

观察性病例报告。

结果

一名 73 岁女性患者因进行性双侧视力下降而就诊。患者为正视眼，就诊时右眼最佳矫正视力为 20/50，左眼为 20/64。患者有腰痛病史，已连续 16 年每天服用盐酸曲马多 200 毫克。通过包括光相干断层扫描血管造影在内的多种模态成像手段，确诊为双侧囊样黄斑水肿。曲马多的摄入量在一个月内逐渐减少，然后完全中断。在 3 个月的随访中，双侧囊样黄斑水肿完全消退，双眼最佳矫正视力均有所提高。