Oak Ridge Center for Risk Analysis, Inc., Oak Ridge, TN.
Department of Epidemiology and Biostatistics, School of Medicine, University of California-San Francisco, San Francisco, CA.
Health Phys. 2021 Mar 1;120(3):278-287. doi: 10.1097/HP.0000000000001313.
This paper documents the estimation of mean heights and body masses, by age and sex, used in development of organ-specific dose conversion coefficients for external radiation for a historical cohort of about 64,000 patients from the Canadian Fluoroscopy Cohort Study. Patients were exposed to repeated fluoroscopy and chest radiography examinations in the course of treatment for tuberculosis in residential medical facilities throughout Canada between 1930 and 1969. Using Canadian national survey data and extensive literature review, mean heights and masses were obtained for the White population of Canada during the time period of interest, and the differences in mean body mass between tuberculosis patients and the general population were estimated. Results in terms of mean height and body mass of Canadian tuberculosis patients, with uncertainties, are reported for selected age groups (children of ages 1, 5, 10, and 15 y and adults age 20+) and for both sexes. Use of estimated average heights and body masses by age and sex permits the adjustment of computerized phantoms for body mass for a given age, thereby increasing the relevance of the organ-specific dose conversion coefficients for the cohort and improving the accuracy of the resulting estimated organ doses.
本文记录了加拿大透视队列研究中约 64000 名患者历史队列的器官特异性剂量转换系数的开发中，按年龄和性别估算的平均身高和体重。这些患者在 1930 年至 1969 年期间，因肺结核在加拿大各地的住院医疗机构中接受了多次透视和胸部 X 光检查。利用加拿大全国调查数据和广泛的文献综述，获得了感兴趣时间段内加拿大白人群体的平均身高和体重，并且估算了肺结核患者与普通人群之间的平均体重差异。报告了按年龄和性别划分的加拿大肺结核患者的平均身高和体重（1、5、10 和 15 岁的儿童以及 20 岁以上的成年人）以及不确定度。按年龄和性别估算的平均身高和体重的使用允许对给定年龄的计算机体模进行体重调整，从而提高了队列器官特异性剂量转换系数的相关性，并提高了由此产生的器官剂量的估计准确性。
