Dizdar Selma, Dzinovic Amra, Gojak Refet, Bakalovic Ganimeta, Selimovic Amina
Pediatric clinic, Clinical center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Clinic for Infectious Diseases, Clinical center of University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Med Arch. 2014 Oct;68(5):317-8. doi: 10.5455/medarh.2014.68.317-318. Epub 2014 Oct 15.
Due to the geographical position of Bosnia and Herzegovina and its socio economic momentum even though the standard vaccination program is carried out, the child population continues to suffer from pulmonary tuberculosis in significant percentage.
The study was retrospective and included patients who were in the period from January 1, 2004 to December 31, 2013 (or the 10 years period) hospitalized at the Department of Pulmonology Pediatric Clinic dually diagnosed with lung TB and start treatment. Data were adopted from available medical records (history of disease).
The aim of the study was to determine the epidemiological and clinical characteristics of tuberculosis of the lungs in children who were hospitalized at the Pediatric Clinic.
In the period from January 1, 2004 to December 31, 2013 there were hospitalized a total of 50 children with a proven active infection with MBT, where it was initiated treatment with a specific therapy. From this number 44% of patients were aged from 5 to 10 years, 22% of patients were aged younger than 5 years. Peak incidence was in 2009. About 66% of patients had a positive history of sick close relative, while 10% of them had a history of contact with other sick person. From baseline 28% of patients were referred to the Department with suspicion of a specific process. From the total 70% of respondents were regularly vaccinated, and 29% of them had a visible BCG scar. In 55% of cases there was anamnestic information - decresed body weight, in 82% of cases the presence of cough, of which 52% of the occurrence of expectoration. In 78% of cases we had positive auscultatory findings of the lungs. In 14% of cases on X-ray of the lungs was noticed changes in terms of the primary complex positive. In this material we had one cavernous and one miliary TB of the lungs. Sputum or gastric lavage was positive in 62% of cases, and Quantiferon because of the lack of the same (in the past) was positive in 34% of cases. All subjects at the time of discharge were classified as recovered. In that period we had proven resistant TB.
Bosnia and Herzegovina belongs to the group of countries with still present and evident TB. In the investigated period of ten years from the pediatric pulmonary TB, usually have suffered small children and adolescents. At moment of discharge, all patients were classified as recovered. In the teste material we did not have proven resistant TB.
由于波斯尼亚和黑塞哥维那的地理位置及其社会经济发展态势,即便实施了标准疫苗接种计划,儿童群体中仍有相当比例的人罹患肺结核。
本研究为回顾性研究,纳入了2004年1月1日至2013年12月31日期间(即10年期间)在儿科肺病诊所住院、被双重诊断为肺结核并开始治疗的患者。数据取自现有的病历(疾病史)。
本研究的目的是确定在儿科诊所住院的儿童肺结核的流行病学和临床特征。
2004年1月1日至2013年12月31日期间,共有50名确诊为活动性结核分枝杆菌感染的儿童住院,并开始接受特定治疗。其中44%的患者年龄在5至10岁之间,22%的患者年龄小于5岁。发病高峰在2009年。约66%的患者有近亲患病史,而其中10%的患者有与其他病人接触的病史。从一开始,28%的患者因怀疑特定病症而被转诊至该科室。在所有受访者中,70%的人按常规接种了疫苗,其中29%的人有可见的卡介苗接种疤痕。55%的病例有体重减轻的既往史,82%的病例有咳嗽症状,其中52%的病例有咳痰现象。78%的病例肺部听诊有阳性发现。14%的病例肺部X线检查显示原发性复合征呈阳性改变。在本研究材料中,有1例肺空洞型和1例粟粒型肺结核。62%的病例痰液或洗胃检查呈阳性,由于过去缺乏相关检查,34%的病例结核菌素释放试验呈阳性。所有受试者出院时均被归类为康复。在此期间,我们确诊了耐药结核病。
波斯尼亚和黑塞哥维那属于结核病仍然存在且明显的国家群体。在调查的十年期间,儿童肺结核患者通常为幼儿和青少年。出院时,所有患者均被归类为康复。在测试材料中,我们未确诊耐药结核病。