Price W A
Northeastern Ohio Universities College of Medicine, Youngstown.
Hillside J Clin Psychiatry. 1987;9(2):225-30.
The antipsychotic effects of verapamil were tested in a double-blind, placebo-controlled, randomized study in 18 patients who met Research Diagnostic Criteria for acute schizophrenia. The antipsychotic effect of verapamil as measured by the Bunney-Hamburg Global Rating Scale were equal to those of haloperidol. Both verapamil and haloperidol were superior to placebo in decreasing psychotic symptoms. The results indicate that verapamil may have clinical utility in the treatment of schizophrenia.
在一项针对18名符合急性精神分裂症研究诊断标准的患者的双盲、安慰剂对照、随机研究中，测试了维拉帕米的抗精神病作用。通过邦尼 - 汉堡总体评定量表测量，维拉帕米的抗精神病作用与氟哌啶醇相当。维拉帕米和氟哌啶醇在减轻精神症状方面均优于安慰剂。结果表明，维拉帕米在精神分裂症治疗中可能具有临床应用价值。
