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一家儿童医院医生中SARS-CoV-2抗体的血清流行率。

Seroprevalence of SARS-CoV-2 antibodies among physicians from a children's hospital.

作者信息

Insúa Claudia, Stedile Graciela, Figueroa Verónica, Hernández Claudia, Svartz Alejandra, Ferrero Fernando, Ossorio María F, Brunetto Oscar

机构信息

División Endocrinología, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.

División Laboratorio Central, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Arch Argent Pediatr. 2020 Dec;118(6):381-385. doi: 10.5546/aap.2020.eng.381.

Abstract

INTRODUCTION

In just a few months, coronavirus disease 2019 (COVID-19) has become a pandemic, causing millions of cases and hundreds of thousands of deaths. Due to its high infectiousness, the health care staff is even more exposed. Nevertheless, there is still very limited information about it, especially among pediatricians.

OBJECTIVE

To assess the seroprevalence of SARSCoV- 2 antibodies among physicians from a children's hospital 3 months after the first case in Argentina. To explore if certain demographic, occupational, and epidemiological characteristics are risk factors for SARS-CoV-2 seropositivity.

METHODS

Cross-sectional study of physicians randomly selected from the list of workers of a children's hospital. All of them were screened for SARS-CoV-2 antibodies by chemiluminescence (immunoglobulins G/M [IgG/IgM]) and their epidemiological history was collected (age, place of residence, professional category, contact with infected people) in order to explore the association between predictors and seropositivity.

RESULTS

A total of 116 physicians were included; their average age was 45.6 ± 13.3 years. Of them, 62.9 % were staff physicians, and the rest, residents; 42.2 % worked in areas designated for direct care of COVID-19 patients. Four (3.5 %) referred contact with infected people without the appropriate protection, and 6 (5.2 %), having traveled to risk areas. SARS-CoV-2 antibodies (IgG) were only detected in one of the professionals. Because of this, it was impossible to assess the association between potential predictors and the presence of SARS-CoV-2 antibodies.

CONCLUSION

It was observed that only 0.9 % of the physicians from a children's hospital had SARS-CoV-2 antibodies.

摘要

引言

在短短几个月内,2019冠状病毒病(COVID-19)已成为大流行病,导致数百万病例和数十万人死亡。由于其高传染性,医护人员面临更高的感染风险。然而,关于这种疾病的信息仍然非常有限,尤其是在儿科医生中。

目的

评估阿根廷首例病例出现3个月后一家儿童医院医生中SARS-CoV-2抗体的血清流行率。探讨某些人口统计学、职业和流行病学特征是否为SARS-CoV-2血清阳性的危险因素。

方法

对从一家儿童医院工作人员名单中随机抽取的医生进行横断面研究。通过化学发光法(免疫球蛋白G/M[IgG/IgM])对所有医生进行SARS-CoV-2抗体筛查,并收集他们的流行病学史(年龄、居住地点、专业类别、与感染者的接触情况),以探讨预测因素与血清阳性之间的关联。

结果

共纳入116名医生;他们的平均年龄为45.6±13.3岁。其中,62.9%为在职医生,其余为住院医生;42.2%在指定用于直接护理COVID-19患者的区域工作。4名(3.5%)医生提到在没有适当防护的情况下与感染者接触,6名(5.2%)医生曾前往高风险地区。仅在一名专业人员中检测到SARS-CoV-2抗体(IgG)。因此,无法评估潜在预测因素与SARS-CoV-2抗体存在之间的关联。

结论

观察到一家儿童医院中只有0.9%的医生有SARS-CoV-2抗体。

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