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失眠老年患者的睡眠误判与短时间和正常客观睡眠时间及认知行为疗法的影响。

Sleep misestimation among older adults suffering from insomnia with short and normal objective sleep duration and the effects of cognitive behavior therapy.

机构信息

Adelaide Institute for Sleep Health: A Flinders Centre for Research Excellence, Flinders University of South Australia, Adelaide, Australia.

National Centre for Sleep Health Services Research, Flinders University, Adelaide, Australia.

出版信息

Sleep. 2021 May 14;44(5). doi: 10.1093/sleep/zsaa250.

DOI:10.1093/sleep/zsaa250
PMID:33231256
Abstract

STUDY OBJECTIVES

Compare the degree of sleep misestimation in older adults with insomnia presenting with objectively short relative to normal sleep duration, and investigate the differential therapeutic response on sleep misestimation between the proposed sleep duration phenotypes to cognitive-behavior therapy for insomnia (CBTi).

METHODS

Ninety-one adults (male = 43, mean age = 63.34, SD = 6.41) with sleep maintenance insomnia were classified as short sleepers (SS; <6 h total sleep time [TST]) or normal sleepers (NS; ≥6 h TST) based on one night of home-based polysomnography. Participants were randomly allocated to CBTi (N = 30 SS, N = 33 NS) or to a wait-list control condition (N = 9 SS, N = 19 NS). Sleep misestimation was calculated as the difference scores of subjective (sleep diary reported) and objective (derived from actigraphy) sleep onset latency (SOL), wake after sleep onset (WASO), and TST at pre- and post-treatment, and 3-month follow-up.

RESULTS

Prior to treatment, perception of SOL, WASO, and TST did not differ between patients with objectively short sleep duration relative to those with objectively normal sleep duration. Patients' perception of WASO and TST, improved immediately following treatment and at 3-month follow-up relative to the waitlist group. These improvements did not differ significantly between those with short or normal objective sleep duration prior to treatment.

CONCLUSIONS

The degree of sleep misestimation is similar for older adults suffering from chronic insomnia with short or normal objective sleep duration. Irrespective of objective sleep duration prior to treatment, CBTi produces significant improvements in sleep perception.

CLINICAL TRIAL REGISTRATION NUMBER

ACTRN12620000883910.

摘要

研究目的

比较失眠症老年人中客观睡眠时间短(相对正常睡眠时间)与客观睡眠时间正常的老年人对睡眠的估计误差程度,并探讨针对失眠认知行为疗法(CBTi)的提出的睡眠时间表型对睡眠估计误差的差异治疗反应。

方法

91 名患有睡眠维持性失眠症的成年人(男性=43 名,平均年龄=63.34 岁,标准差=6.41 岁)根据一夜家庭多导睡眠图分为短睡眠者(SS;总睡眠时间[TST] <6 小时)或正常睡眠者(NS;TST ≥6 小时)。参与者被随机分配到 CBTi(N=30 SS,N=33 NS)或等待名单对照条件(N=9 SS,N=19 NS)。睡眠估计误差是通过主观(睡眠日记报告)和客观(来自活动记录仪)的睡眠潜伏期(SOL)、睡眠后觉醒(WASO)和 TST 的差值计算得出,在治疗前、治疗后和 3 个月随访时进行测量。

结果

在治疗前,与客观睡眠时间正常的患者相比,客观睡眠时间较短的患者对 SOL、WASO 和 TST 的感知没有差异。治疗后和 3 个月随访时,患者对 WASO 和 TST 的感知均立即改善,与等待名单组相比。在治疗前,与客观睡眠时长较短或正常的患者相比,这些改善在客观睡眠时长较短或正常的患者之间没有显著差异。

结论

对于患有慢性失眠症且客观睡眠时间较短或正常的老年人,睡眠估计误差的程度相似。无论治疗前的客观睡眠时间如何,CBTi 都能显著改善睡眠感知。

临床试验注册号

ACTRN12620000883910。

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