Agache P, Amblard P, Moulin G, Barrière H, Texier L, Beylot C, Bergoend H
University Department of Dermatology, Hôpital St-Jacques, Besançon, France.
J Antimicrob Chemother. 1987 Nov;20 Suppl B:153-6. doi: 10.1093/jac/20.suppl_b.153.
In a double blind randomised investigation in 76 patients, roxithromycin (150 mg bd) and doxycycline (200 mg once daily) were compared in two groups of patients who were well-matched for age, sex, body weight, diagnosis, duration and severity of disease and associated pathological conditions, with infected skin conditions. Clinical effectiveness was 92% for roxithromycin and 82% for doxycycline, and bacteriological effectiveness also 92% and 82% respectively, the differences not being statistically significant.