Agache P, Amblard P, Moulin G, Barrière H, Texier L, Beylot C, Bergoend H
University Department of Dermatology, Hôpital St-Jacques, Besançon, France.
J Antimicrob Chemother. 1987 Nov;20 Suppl B:153-6. doi: 10.1093/jac/20.suppl_b.153.
In a double blind randomised investigation in 76 patients, roxithromycin (150 mg bd) and doxycycline (200 mg once daily) were compared in two groups of patients who were well-matched for age, sex, body weight, diagnosis, duration and severity of disease and associated pathological conditions, with infected skin conditions. Clinical effectiveness was 92% for roxithromycin and 82% for doxycycline, and bacteriological effectiveness also 92% and 82% respectively, the differences not being statistically significant.
在一项针对76例患者的双盲随机研究中，将罗红霉素（150毫克，每日两次）和强力霉素（200毫克，每日一次）在两组年龄、性别、体重、诊断、疾病持续时间和严重程度以及相关病理状况相匹配的感染性皮肤病患者中进行比较。罗红霉素的临床有效率为92%，强力霉素为82%；细菌学有效率分别为92%和82%，差异无统计学意义。
