Ridgway G L
Department of Clinical Microbiology, University College Hospital, London, U.K.
J Antimicrob Chemother. 1987 Nov;20 Suppl B:7-11. doi: 10.1093/jac/20.suppl_b.7.
The in-vitro activity of roxithromycin against Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Treponema pallidum, Gardnerella vaginalis and Haemophilus ducreyi is reviewed. Roxithromycin demonstrated equivalent activity to erythromycin against N. gonorrhoeae, C. trachomatis, M. hominis, U. urealyticum, G. vaginalis and H. ducreyi. In a rabbit model for syphilis, potentially useful activity against T. pallidum has been demonstrated.
综述了罗红霉素对淋病奈瑟菌、沙眼衣原体、人型支原体、解脲脲原体、梅毒螺旋体、阴道加德纳菌和杜克雷嗜血杆菌的体外活性。罗红霉素对淋病奈瑟菌、沙眼衣原体、人型支原体、解脲脲原体、阴道加德纳菌和杜克雷嗜血杆菌显示出与红霉素相当的活性。在梅毒兔模型中，已证明罗红霉素对梅毒螺旋体具有潜在的有效活性。
