Ophthalmic Surg Lasers Imaging Retina. 2020 Nov 1;51(11):640-647. doi: 10.3928/23258160-20201104-06.
BACKGROUND AND OBJECTİVE: The purpose of this study is to compare the morphological features of type 1 choroidal neovascularization (CNV) in eyes with age-related macular degeneration (AMD) and pachychoroid neovasculopathy (PNV) using optical coherence tomography angiography (OCTA). PATİENTS AND METHODS: Nineteen eyes of 17 patients with PNV and 30 eyes of 30 patients with AMD were evaluated. The size and area of CNV and morphological patterns during a 6-month period were analyzed using optical coherence tomography angiography. RESULTS: The presence of a feeder vessel was more common in AMD than in PNV. Indistinct pattern was more common in PNV than AMD. Pruned vascular tree pattern was rare in PNV eyes during follow-up. The mean size and flow of selected CNV area was significantly smaller in PNV group. CONCLUSİON: This study demonstrated that type 1 CNVs in the PNV group is characterized by a smaller area. Morphologic pattern differences between them might be explained by different etiopathogenesis under these circumstances. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:640-647.].
本研究旨在通过光相干断层扫描血管造影术(OCTA)比较年龄相关性黄斑变性(AMD)和厚脉络膜新生血管(PNV)患者 1 型脉络膜新生血管(CNV)的形态特征。
评估了 17 名 PNV 患者的 19 只眼和 30 名 AMD 患者的 30 只眼。使用 OCTA 分析了 6 个月期间 CNV 的大小和面积以及形态模式。
AMD 中存在供养血管比 PNV 更常见。PNV 中不明显模式比 AMD 更常见。随访中 PNV 眼修剪血管树模式罕见。PNV 组选择的 CNV 区域的平均大小和流量明显较小。
本研究表明,PNV 组的 1 型 CNV 特征是面积较小。在这种情况下,它们之间的形态模式差异可能由不同的病因发病机制解释。