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一项前瞻性纵向调查研究了新诊断癌症患者在治愈性化疗期间和之后的就业和工作结果:威斯康星肿瘤网络研究。

Results from a prospective longitudinal survey of employment and work outcomes in newly diagnosed cancer patients during and after curative-intent chemotherapy: A Wisconsin Oncology Network study.

机构信息

University of Wisconsin Carbone Cancer Center, Madison, Wisconsin.

Division of Hematology/Oncology & Palliative Care, Department of Medicine, University of Wisconsin, Madison, Wisconsin.

出版信息

Cancer. 2021 Mar 1;127(5):801-808. doi: 10.1002/cncr.33311. Epub 2020 Nov 24.

Abstract

BACKGROUND

Postcancer work limitations may affect a substantial proportion of patients and contribute to the "financial toxicity" of cancer treatment. The degree and nature of work limitations and employment outcomes are poorly understood for cancer patients, particularly in the immediate period of transition after active treatment. We prospectively examined employment, work ability, and work limitations during and after treatment.

METHODS

A total of 120 patients receiving curative therapy who were employed prior to their cancer diagnosis and who intended to work during or after end of treatment (EOT) completed surveys at baseline (pretreatment), EOT, and 3, 6, and 12 months after EOT. Surveys included measures of employment, work ability, and work limitations. Descriptive statistics (frequencies, percentages, means with standard deviations) were calculated.

RESULTS

A total of 111 participants completed the baseline survey. On average, participants were 48 years of age and were mostly white (95%) and female (82%) with a diagnosis of breast cancer (69%). Full-time employment decreased during therapy (from 88% to 50%) and returned to near prediagnosis levels by 12-month follow-up (78%). Work-related productivity loss due to health was high during treatment.

CONCLUSIONS

This study is the first to report the effects of curative intent cancer therapy on employment, work ability, and work limitations both during and after treatment. Perceived work ability was generally high overall 12 months after EOT, although a minority reported persistent difficulty. A prospective analysis of factors (eg, job type, education, symptoms) most associated with work limitations is underway to assist in identifying at-risk patients.

摘要

背景

癌症治疗后的工作限制可能会影响相当一部分患者,并导致癌症治疗的“经济毒性”。癌症患者的工作限制程度和性质以及就业结果知之甚少,尤其是在积极治疗结束后的过渡期间。我们前瞻性地检查了治疗期间和治疗后的就业、工作能力和工作限制。

方法

共有 120 名接受根治性治疗的患者在癌症诊断前就业,并计划在治疗结束(EOT)期间或之后工作,他们在基线(治疗前)、EOT 以及 EOT 后 3、6 和 12 个月完成了调查。调查包括就业、工作能力和工作限制的测量。计算了描述性统计数据(频率、百分比、平均值和标准差)。

结果

共有 111 名参与者完成了基线调查。平均而言,参与者年龄为 48 岁,大多数是白人(95%)和女性(82%),诊断为乳腺癌(69%)。全职就业在治疗期间下降(从 88%降至 50%),并在 12 个月随访时恢复到接近诊断前的水平(78%)。治疗期间由于健康原因导致工作相关的生产力损失很高。

结论

这项研究是首次报告根治性癌症治疗对治疗期间和治疗后就业、工作能力和工作限制的影响。在 EOT 后 12 个月,整体上对工作能力的感知较高,尽管少数人报告持续存在困难。正在对与工作限制最相关的因素(例如工作类型、教育、症状)进行前瞻性分析,以帮助识别高危患者。

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