Department of Physical Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Department of Physical Therapy, Rofeideh Rehabilitation Hospital Clinical Research Development Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Appl Neuropsychol Adult. 2022 Sep-Oct;29(5):1095-1102. doi: 10.1080/23279095.2020.1848836. Epub 2020 Nov 24.
The aim of this study was to culturally adapt and validate Leeds assessment of neuropathic symptoms and signs (LANSS) and self-report LANSS (S-LANSS) tools. Patients with chronic pain ( = 206) were categorized into neuropathic pain (NeP) ( = 101) or non-NeP ( = 105). After the translation process, both questionnaires and the Persian Douleur Neuropathique 4 (P-DN4) were administered to patients to assess the clinometric properties. The mean overall score of both tools was significantly higher in the NeP group ( < 0.01). Test-retest reliability analysis of the overall score of the Persian (P)-LANSS and PS-LANSS were 0.99 and 0.98, respectively. α-Cronbach value for P-LANSS and PS-LANSS were 0.64 and 0.61, respectively. Factor analysis of both questionnaires yielded two components explaining most of the observable variance. The P-LANSS was significantly correlated with PS-LANSS and P-DN4 (ρ = 0.92, = 0.01, for both). PS-LANSS was also significantly correlated with P-DN4 ( = 0.79, = 0.01). Both tools successfully diagnosed NeP patients at the cutoff point of ≥12 with 88.12% sensitivity and 76.19% specificity for P-LANSS and 83.17% sensitivity and 95.24% specificity for PS-LANSS. P-LANSS and PS-LANSS are reliable and valid tools to identify NeP component in chronic pain patients. PS-LANSS was found to be an acceptable alternative for P-LANSS.
本研究旨在对 Leeds 评估周围神经病理性症状和体征（LANSS）工具及其自评版（S-LANSS）进行文化调适和验证。将慢性疼痛患者（ = 206）分为神经病理性疼痛（NeP）组（ = 101）和非神经病理性疼痛（NeP）组（ = 105）。在翻译过程之后，将两种问卷和 Persian Douleur Neuropathique 4（P-DN4）一起提供给患者，以评估临床计量学特性。两种工具的总体评分在 NeP 组中均显著更高（ < 0.01）。波斯语版（P）-LANSS 和 PS-LANSS 总体评分的重测信度分析分别为 0.99 和 0.98。P-LANSS 和 PS-LANSS 的 α-Cronbach 值分别为 0.64 和 0.61。对两种问卷的因子分析得出了两个解释大部分可观测方差的成分。P-LANSS 与 PS-LANSS 和 P-DN4 显著相关（ρ = 0.92， = 0.01，两者均为）。PS-LANSS 也与 P-DN4 显著相关（ = 0.79， = 0.01）。两种工具在 P-LANSS 的 cutoff 值≥12 时成功诊断出 NeP 患者，敏感性为 88.12%，特异性为 76.19%；PS-LANSS 的敏感性为 83.17%，特异性为 95.24%。P-LANSS 和 PS-LANSS 是可靠和有效的工具，可用于识别慢性疼痛患者的 NeP 成分。PS-LANSS 被发现是 P-LANSS 的可接受替代方法。
